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Gene: LOC100984072 (taste receptor type 2 member 46) Pan paniscus

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Symbol:

LOC100984072 (Ensembl: TAS2R46)

Name:

taste receptor type 2 member 46 (Ensembl:taste 2 receptor member 46)

RGD ID:

11949768

Description:

ENCODES a protein that exhibits bitter taste receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN detection of chemical stimulus involved in sensory perception of bitter taste (inferred); G protein-coupled receptor signaling pathway (inferred); sensory perception of taste (inferred); FOUND IN ciliary membrane (inferred); cilium (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

T2R46; TAS2R; TAS2R46; taste 2 receptor member 46; taste receptor T2R46

RGD Orthologs

Human

Dog

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	16,536,075 - 16,537,040 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	16,532,852 - 16,533,796 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	11,093,272 - 11,094,204 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	11,359,157 - 11,360,089 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	11,359,157 - 11,360,086 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of bitter taste (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of taste (IEA)

Cellular Component

ciliary membrane (IEA)

cilium (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

bitter taste receptor activity (IEA)

G protein-coupled receptor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC100984072
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	16,536,075 - 16,537,040 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	16,532,852 - 16,533,796 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	11,093,272 - 11,094,204 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	11,359,157 - 11,360,089 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	11,359,157 - 11,360,086 (-)	Ensembl	panpan1.1		panPan2

TAS2R46
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	11,061,365 - 11,062,294 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	11,061,365 - 11,062,294 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	11,213,964 - 11,214,893 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	11,105,231 - 11,106,160 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	11,105,261 - 11,106,160	NCBI
Celera	12	16,363,837 - 16,364,766 (-)	NCBI		Celera
Cytogenetic Map	12	p13.2	NCBI
HuRef	12	10,944,179 - 10,945,108 (-)	NCBI		HuRef
CHM1_1	12	11,185,435 - 11,186,364 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	10,936,559 - 10,937,488 (-)	NCBI		T2T-CHM13v2.0

CAFA-T2R43
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	34,792,712 - 34,793,761 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	34,792,712 - 34,793,761 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	11,654,454 - 11,655,503 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	35,100,723 - 35,101,772 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	35,100,723 - 35,101,772 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	34,990,295 - 34,991,344 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	34,940,613 - 34,941,662 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	11,382,999 - 11,384,048 (-)	NCBI		UU_Cfam_GSD_1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003829606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY677150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY724848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JARIFH020000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000027037 ⟹ ENSPPAP00000006165

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	11,359,157 - 11,360,086 (-)	Ensembl

RefSeq Acc Id:

XM_003829606 ⟹ XP_003829654

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	16,536,075 - 16,537,040 (-)	NCBI
NHGRI_mPanPan1	12	16,532,852 - 16,533,796 (-)	NCBI
Mhudiblu_PPA_v0	12	11,093,272 - 11,094,204 (-)	NCBI
PanPan1.1	12	11,359,157 - 11,360,089 (-)	NCBI

Sequence:

show sequence

GACATGATAACTTTTCTGCCCATCATTTTTTCCATTCTAATAGTGGTTACATTTGTGATTGGAA
ATTTTGCTAATGGCTTCATAGCATTGGCAAATTCCATTGAGTGGTTCAAGAGACAAAAGATCTC
TTTTGCTGACCAAATTCTCACTGCTCTGGCAGTCTCCAGAGTTGGTTTACTCTGGGTATTATTA
TTAAATTGGTATGCAACTGAGTTGAATCCAGCTTTTTACAGTATAGAAGTAAGAATTACTGCTT
ATAATCTCTGGGCAGTAATCAACCATTTCAGCAACTGGCTTGCTACTAGCCTCAGCATATTTTA
TTTGCTCAAGATTGCCAATTTCTCCAACCTTATTTTTCTTCGCTTAAAGAGGAGAGTTAAGAGT
GTTGTTCTGGTGATACTGTTGGGGCCTTTGCTATTTTTGGTTTGTCATCTTTTTGTGATAAACA
TGAATCAGATTATATGGACAAAAGAATATGAAGGAAACATGACTTGGAAGATCAAATTGAGGAG
TGCAATGTACCTTTCAAATACAACGGTAACCATCCTAGCAAACTTAGTTCCCTTCACTCTGACC
CTGATATCTTTTCTGCTGTTAATCTGTTCTCTGTGTAAACATCTCAAGAAGATGCAGCTCCATG
GCAAAGGATCTCAAGATCCCAGCATGAAGGTCCACATAAAAGCTTTGCAAACTGTGACCTCCTT
CCTCTTGTTATGTGCCATTTACTTTCTGTCCATAATCATGTCAGTTTGGAGTTTTGAGAGTCTG
GAAAACAAACCTGTCTTCATGTTCTGCGAAGCTATTACATTCAGCTATCCTTCAACCCACCCAT
TCATCCTGATTTGGGGAAACAAGAAGCTAAAGCAGACTTTTCTTTCAGTTTTGTGGCATGTGAG
GTACTGGGTGAAAGGAGAGAAGCCTTCATCTCCATAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_003829654	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAU21078	(Get FASTA)	NCBI Sequence Viewer
	AAV28578	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000006165.1
GenBank Protein	Q646E1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_003829654 ⟸ XM_003829606

- UniProtKB:

Q646E1 (UniProtKB/Swiss-Prot), Q5Y4Z7 (UniProtKB/Swiss-Prot), A0A2R8ZNR4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MITFLPIIFSILIVVTFVIGNFANGFIALANSIEWFKRQKISFADQILTALAVSRVGLLWVLLL
NWYATELNPAFYSIEVRITAYNLWAVINHFSNWLATSLSIFYLLKIANFSNLIFLRLKRRVKSV
VLVILLGPLLFLVCHLFVINMNQIIWTKEYEGNMTWKIKLRSAMYLSNTTVTILANLVPFTLTL
ISFLLLICSLCKHLKKMQLHGKGSQDPSMKVHIKALQTVTSFLLLCAIYFLSIIMSVWSFESLE
NKPVFMFCEAITFSYPSTHPFILIWGNKKLKQTFLSVLWHVRYWVKGEKPSSP

hide sequence

Ensembl Acc Id:

ENSPPAP00000006165 ⟸ ENSPPAT00000027037

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000024519	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000027037.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	TAS2R	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	pps:100984072	UniProtKB/TrEMBL
NCBI Gene	LOC100984072	ENTREZGENE
PANTHER	TASTE RECEPTOR TYPE 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TASTE RECEPTOR TYPE 2 MEMBER 46	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	TAS2R	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A2R8ZNR4	ENTREZGENE, UniProtKB/TrEMBL
	Q5Y4Z7	ENTREZGENE
	Q646E1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q5Y4Z7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-07-01	LOC100984072	taste receptor type 2 member 46	TAS2R46	taste 2 receptor member 46	Symbol and/or name change	5135510	APPROVED
2018-05-08	TAS2R46	taste 2 receptor member 46	LOC100984072	taste receptor type 2 member 46	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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