RS1 (retinoschisin 1) - Rat Genome Database

Name: RS1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: RS1 (retinoschisin 1) Pan paniscus

Analyze

Symbol:

RS1

Name:

retinoschisin 1

RGD ID:

11925031

Description:

ENCODES a protein that exhibits phosphatidylcholine binding (ortholog); phosphatidylethanolamine binding (ortholog); phospholipid binding (ortholog); INVOLVED IN retina layer formation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Christianson syndrome (ortholog); Coffin-Lowry syndrome (ortholog); FOUND IN cell surface (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

retinoschisin

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RS1 (retinoschisin 1)	NCBI	Ortholog
Mus musculus (house mouse):	Rs1 (retinoschisis (X-linked, juvenile) 1 (human))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Rs1 (retinoschisin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RS1 (retinoschisin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rs1 (retinoschisin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RS1 (retinoschisin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RS1 (retinoschisin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rs1 (retinoschisin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	20,433,581 - 20,458,436 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	20,433,137 - 20,461,828 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	11,259,222 - 11,282,289 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	18,624,687 - 18,657,315 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	18,624,687 - 18,657,315 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Christianson syndrome (ISO)

Coffin-Lowry syndrome (ISO)

developmental and epileptic encephalopathy 1 (ISO)

developmental and epileptic encephalopathy 2 (ISO)

fundus dystrophy (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

glycogen storage disease IXA (ISO)

Nance-Horan syndrome (ISO)

Neurodevelopmental Disorders (ISO)

Nicolaides-Baraitser syndrome (ISO)

Pyruvate Dehydrogenase E1 Alpha Deficiency (ISO)

retinoschisis (ISO)

Rett Syndrome, Atypical (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

West syndrome (ISO)

X-linked juvenile retinoschisis 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein homooligomerization (IEA)

retina layer formation (IEA,ISO)

visual perception (IEA)

Cellular Component

cell surface (IEA,ISO)

external side of plasma membrane (IEA)

extracellular region (IEA)

extracellular space (IEA)

neuron to neuron synapse (IEA)

photoreceptor inner segment (IEA)

protein-containing complex (IEA)

Molecular Function

phosphatidylcholine binding (ISO)

phosphatidylethanolamine binding (ISO)

phosphatidylinositol-3,4,5-trisphosphate binding (IEA)

phosphatidylinositol-3,4-bisphosphate binding (IEA)

phosphatidylinositol-3,5-bisphosphate binding (IEA)

phosphatidylinositol-3-phosphate binding (IEA)

phosphatidylinositol-4,5-bisphosphate binding (IEA)

phosphatidylinositol-4-phosphate binding (IEA)

phosphatidylinositol-5-phosphate binding (IEA)

phosphatidylserine binding (IEA)

phospholipid binding (ISO)

protein-containing complex binding (IEA)

References

Genomics

Comparative Map Data

RS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	20,433,581 - 20,458,436 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	20,433,137 - 20,461,828 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	11,259,222 - 11,282,289 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	18,624,687 - 18,657,315 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	18,624,687 - 18,657,315 (-)	Ensembl	panpan1.1		panPan2

RS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	18,639,688 - 18,672,108 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	18,639,688 - 18,672,108 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	18,657,808 - 18,690,228 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	18,567,729 - 18,600,150 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	18,417,466 - 18,449,886	NCBI
Celera	X	22,777,900 - 22,810,314 (-)	NCBI		Celera
Cytogenetic Map	X	p22.13	NCBI
HuRef	X	16,411,987 - 16,443,999 (-)	NCBI		HuRef
CHM1_1	X	18,688,889 - 18,721,309 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	18,222,290 - 18,254,713 (-)	NCBI		T2T-CHM13v2.0

Rs1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	159,548,815 - 159,584,800 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	159,551,009 - 159,582,659 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	160,765,819 - 160,799,663 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	160,768,013 - 160,799,663 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	157,205,945 - 157,237,595 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	156,112,118 - 156,143,768 (+)	NCBI		MGSCv36	mm8
Celera	X	144,007,814 - 144,039,864 (+)	NCBI		Celera
Cytogenetic Map	X	F4	NCBI
cM Map	X	73.95	NCBI

Rs1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	37,771,135 - 37,800,894 (-)	NCBI		GRCr8
mRatBN7.2	X	33,962,440 - 33,992,203 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	33,963,657 - 33,992,115 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	35,125,011 - 35,153,478 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	38,586,858 - 38,615,312 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	36,262,164 - 36,290,631 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	35,749,957 - 35,777,243 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	35,749,957 - 35,777,243 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	36,077,773 - 36,106,448 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	55,242,654 - 55,266,251 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	34,650,786 - 34,679,172 (-)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

RS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	14,727,016 - 14,749,674 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	14,727,062 - 14,749,492 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	14,692,941 - 14,703,063 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	14,692,682 - 14,716,577 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	14,751,342 - 14,764,123 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	14,744,546 - 14,757,322 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	14,808,349 - 14,821,138 (-)	NCBI		UU_Cfam_GSD_1.0

Rs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	7,795,248 - 7,824,783 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936844	284,141 - 314,545 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936844	284,938 - 314,524 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	15,085,050 - 15,109,243 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	15,080,972 - 15,099,426 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	16,293,478 - 16,317,820 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	17,089,382 - 17,105,145 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	17,089,598 - 17,118,447 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	18,977,893 - 19,004,727 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rs1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624829	3,485,708 - 3,518,447 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624829	3,485,635 - 3,498,431 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_034950489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055106655	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000059359 ⟹ ENSPPAP00000036467

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	18,624,687 - 18,657,315 (-)	Ensembl

RefSeq Acc Id:

XM_055106655 ⟹ XP_054962630

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	20,433,581 - 20,458,436 (-)	NCBI
NHGRI_mPanPan1	X	20,433,137 - 20,461,828 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_054962630	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000036467.1

RefSeq Acc Id:

ENSPPAP00000036467 ⟸ ENSPPAT00000059359

RefSeq Acc Id:

XP_054962630 ⟸ XM_055106655

Protein Domains

F5/8 type C

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040996	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000059359.1	UniProtKB/TrEMBL
Gene3D-CATH	Galactose-binding domain-like	UniProtKB/TrEMBL
InterPro	FA58C	UniProtKB/TrEMBL
	Galactose-bd-like_sf	UniProtKB/TrEMBL
NCBI Gene	RS1	ENTREZGENE
PANTHER	MULTICOPPER OXIDASE-RELATED	UniProtKB/TrEMBL
	RETINOSCHISIN	UniProtKB/TrEMBL
Pfam	F5_F8_type_C	UniProtKB/TrEMBL
PROSITE	FA58C_1	UniProtKB/TrEMBL
	FA58C_3	UniProtKB/TrEMBL
SMART	FA58C	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49785	UniProtKB/TrEMBL
UniProt	A0A2R9CDT4_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM