FLAD1 (flavin adenine dinucleotide synthetase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: FLAD1 (flavin adenine dinucleotide synthetase 1) Pan paniscus
Analyze
Symbol: FLAD1
Name: flavin adenine dinucleotide synthetase 1
RGD ID: 11884479
Description: ENCODES a protein that exhibits ATP binding (inferred); FMN adenylyltransferase activity (inferred); identical protein binding (inferred); INVOLVED IN FAD biosynthetic process (inferred); flavin adenine dinucleotide biosynthetic process (inferred); riboflavin metabolic process (inferred); PARTICIPATES IN riboflavin metabolic pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAD synthase; FAD1 flavin adenine dinucleotide synthetase homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,847,721 - 94,857,210 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,579,801 - 94,589,336 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,331,795 - 130,341,279 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,941,467 - 133,950,399 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,941,665 - 133,950,399 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FLAD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,847,721 - 94,857,210 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,579,801 - 94,589,336 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,331,795 - 130,341,279 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,941,467 - 133,950,399 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,941,665 - 133,950,399 (+)Ensemblpanpan1.1panPan2
FLAD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,983,344 - 154,993,111 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,983,338 - 154,993,111 (+)EnsemblGRCh38hg38GRCh38
GRCh371154,955,820 - 154,965,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361153,222,441 - 153,232,211 (+)NCBINCBI36Build 36hg18NCBI36
Celera1128,026,794 - 128,036,611 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1126,317,512 - 126,327,328 (+)NCBIHuRef
CHM1_11156,352,143 - 156,361,989 (+)NCBICHM1_1
T2T-CHM13v2.01154,122,705 - 154,132,467 (+)NCBIT2T-CHM13v2.0
Flad1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,309,980 - 89,319,188 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,308,311 - 89,319,177 (-)EnsemblGRCm39 Ensembl
GRCm38389,402,673 - 89,411,881 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,401,004 - 89,411,870 (-)EnsemblGRCm38mm10GRCm38
MGSCv37389,206,595 - 89,215,785 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,486,931 - 89,497,799 (-)NCBIMGSCv36mm8
Celera389,437,733 - 89,446,924 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.1NCBI
Flad1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,117,183 - 177,126,650 (-)NCBIGRCr8
mRatBN7.22174,819,451 - 174,828,921 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,819,453 - 174,828,977 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2181,964,992 - 181,974,456 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02179,987,368 - 179,996,832 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,587,927 - 174,597,415 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02188,726,994 - 188,736,462 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,726,994 - 188,736,462 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,141,438 - 208,150,742 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,598,068 - 181,607,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2168,760,189 - 168,769,645 (-)NCBICelera
Cytogenetic Map2q34NCBI
Flad1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,487,818 - 1,497,839 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,487,929 - 1,495,808 (+)NCBIChiLan1.0ChiLan1.0
FLAD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,489,045 - 42,494,524 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,489,061 - 42,494,471 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,980,121 - 41,985,607 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,358,973 - 42,364,457 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,358,975 - 42,364,447 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,138,669 - 42,144,153 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,192,497 - 42,197,981 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,475,856 - 42,481,340 (-)NCBIUU_Cfam_GSD_1.0
Flad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,499,589 - 25,505,527 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,530,006 - 4,536,730 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,530,007 - 4,535,909 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLAD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,807,287 - 94,813,575 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,807,280 - 94,813,512 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,563,686 - 103,569,836 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FLAD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,838,130 - 8,846,654 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl208,837,892 - 8,846,043 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,172,113 - 8,181,268 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flad1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,496,448 - 2,503,180 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,496,448 - 2,503,277 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000018091   ⟹   ENSPPAP00000003913
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1133,941,665 - 133,950,399 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000018096   ⟹   ENSPPAP00000003915
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1133,946,110 - 133,949,950 (+)Ensembl
RefSeq Acc Id: XM_003817089   ⟹   XP_003817137
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,847,721 - 94,857,210 (-)NCBI
NHGRI_mPanPan1194,579,801 - 94,589,336 (-)NCBI
Mhudiblu_PPA_v01130,331,795 - 130,341,279 (+)NCBI
PanPan1.11133,941,467 - 133,950,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008970274   ⟹   XP_008968522
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,847,721 - 94,856,856 (-)NCBI
NHGRI_mPanPan1194,579,801 - 94,588,985 (-)NCBI
Mhudiblu_PPA_v01130,332,143 - 130,341,279 (+)NCBI
PanPan1.11133,941,918 - 133,950,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008970275   ⟹   XP_008968523
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,847,721 - 94,857,131 (-)NCBI
NHGRI_mPanPan1194,579,801 - 94,589,222 (-)NCBI
Mhudiblu_PPA_v01130,331,905 - 130,341,279 (+)NCBI
PanPan1.11133,941,665 - 133,950,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008970276   ⟹   XP_008968524
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,847,721 - 94,857,154 (-)NCBI
NHGRI_mPanPan1194,579,801 - 94,589,222 (-)NCBI
Mhudiblu_PPA_v01130,331,905 - 130,341,279 (+)NCBI
PanPan1.11133,941,568 - 133,950,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034936609   ⟹   XP_034792500
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,847,721 - 94,857,096 (-)NCBI
NHGRI_mPanPan1194,579,801 - 94,589,222 (-)NCBI
Mhudiblu_PPA_v01130,331,905 - 130,341,279 (+)NCBI
RefSeq Acc Id: XM_063604873   ⟹   XP_063460943
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,847,721 - 94,857,140 (-)NCBI
RefSeq Acc Id: XP_003817137   ⟸   XM_003817089
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZFY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008968524   ⟸   XM_008970276
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008968523   ⟸   XM_008970275
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008968522   ⟸   XM_008970274
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034792500   ⟸   XM_034936609
- Peptide Label: isoform X5
Ensembl Acc Id: ENSPPAP00000003913   ⟸   ENSPPAT00000018091
Ensembl Acc Id: ENSPPAP00000003915   ⟸   ENSPPAT00000018096
RefSeq Acc Id: XP_063460943   ⟸   XM_063604873
- Peptide Label: isoform X6
Protein Domains
MoaB/Mog


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000016509 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000018091.1 UniProtKB/TrEMBL
  ENSPPAT00000018096.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
  3.40.980.10 UniProtKB/TrEMBL
InterPro FAD_synth_MoaB/Mog-bd UniProtKB/TrEMBL
  MoaB/Mog-like_dom_sf UniProtKB/TrEMBL
  MoaB/Mog_dom UniProtKB/TrEMBL
  PAPS_reduct UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
KEGG Report pps:100994508 UniProtKB/TrEMBL
NCBI Gene FLAD1 ENTREZGENE
PANTHER FAD SYNTHASE UniProtKB/TrEMBL
  FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE UniProtKB/TrEMBL
Pfam MoCF_biosynth UniProtKB/TrEMBL
  PAPS_reduct UniProtKB/TrEMBL
PIRSF MPTbdFAD UniProtKB/TrEMBL
SMART MoCF_biosynth UniProtKB/TrEMBL
Superfamily-SCOP Adenine nucleotide alpha hydrolases-like UniProtKB/TrEMBL
  SSF53218 UniProtKB/TrEMBL
UniProt A0A2R8ZFY8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZGE3_PANPA UniProtKB/TrEMBL