TUBB8 (tubulin beta 8 class VIII) - Rat Genome Database

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Gene: TUBB8 (tubulin beta 8 class VIII) Pan paniscus
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Symbol: TUBB8
Name: tubulin beta 8 class VIII
RGD ID: 11878123
Description: ENCODES a protein that exhibits double-stranded RNA binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN oocyte maturation (ortholog); spindle assembly involved in female meiosis (ortholog); ASSOCIATED WITH Female Infertility (ortholog); genetic disease (ortholog); Oocyte Maturation Defect 2 (ortholog); FOUND IN meiotic spindle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubulin beta-8 chain
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2812,543,353 - 12,573,253 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11012,548,675 - 12,578,583 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01056,937 - 61,125 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110140,033 - 142,500 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10140,194 - 142,372 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TUBB8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2812,543,353 - 12,573,253 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11012,548,675 - 12,578,583 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01056,937 - 61,125 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110140,033 - 142,500 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10140,194 - 142,372 (-)Ensemblpanpan1.1panPan2
TUBB8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381046,455 - 76,621 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1046,888 - 74,163 (-)EnsemblGRCh38hg38GRCh38
GRCh371092,828 - 122,561 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361082,997 - 85,178 (-)NCBINCBI36Build 36hg18NCBI36
Celera1036,106 - 38,782 (-)NCBICelera
Cytogenetic Map10p15.3NCBI
HuRef1037,535 - 39,885 (-)NCBIHuRef
CHM1_11092,903 - 95,253 (-)NCBICHM1_1
T2T-CHM13v2.01039,271 - 69,557 (-)NCBIT2T-CHM13v2.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000040474   ⟹   ENSPPAP00000017760
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10140,194 - 142,372 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000040476   ⟹   ENSPPAP00000017762
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10140,194 - 142,372 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000040484   ⟹   ENSPPAP00000017770
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10141,187 - 142,372 (-)Ensembl
RefSeq Acc Id: XM_055092340   ⟹   XP_054948315
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2812,543,353 - 12,573,250 (-)NCBI
NHGRI_mPanPan11012,548,675 - 12,578,578 (-)NCBI
RefSeq Acc Id: XM_063607221   ⟹   XP_063463291
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2812,543,353 - 12,573,253 (-)NCBI
RefSeq Acc Id: XM_063607222   ⟹   XP_063463292
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2812,543,353 - 12,573,253 (-)NCBI
RefSeq Acc Id: XM_063607223   ⟹   XP_063463293
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2812,543,353 - 12,573,250 (-)NCBI
Ensembl Acc Id: ENSPPAP00000017770   ⟸   ENSPPAT00000040484
Ensembl Acc Id: ENSPPAP00000017760   ⟸   ENSPPAT00000040474
Ensembl Acc Id: ENSPPAP00000017762   ⟸   ENSPPAT00000040476
RefSeq Acc Id: XP_054948315   ⟸   XM_055092340
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B2G9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063463292   ⟸   XM_063607222
- Peptide Label: isoform X1
- UniProtKB: A0A2R9APU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063463291   ⟸   XM_063607221
- Peptide Label: isoform X1
- UniProtKB: A0A2R9APU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063463293   ⟸   XM_063607223
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B2G9 (UniProtKB/TrEMBL)
Protein Domains
Tubulin/FtsZ 2-layer sandwich   Tubulin/FtsZ GTPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031982 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAG00000034369 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040474.1 UniProtKB/TrEMBL
  ENSPPAT00000040476.1 UniProtKB/TrEMBL
  ENSPPAT00000040484.1 UniProtKB/TrEMBL
  ENSPPAT00000045156.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.600 UniProtKB/TrEMBL
  3.30.1330.20 UniProtKB/TrEMBL
  3.40.50.1440 UniProtKB/TrEMBL
InterPro Beta-tubulin_BS UniProtKB/TrEMBL
  Beta_tubulin UniProtKB/TrEMBL
  Tub_FtsZ_C UniProtKB/TrEMBL
  Tubulin UniProtKB/TrEMBL
  Tubulin/FtsZ-like_C UniProtKB/TrEMBL
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/TrEMBL
  Tubulin/FtsZ_GTPase_sf UniProtKB/TrEMBL
  Tubulin_C UniProtKB/TrEMBL
  Tubulin_CS UniProtKB/TrEMBL
  Tubulin_FtsZ_GTPase UniProtKB/TrEMBL
NCBI Gene TUBB8 ENTREZGENE
PANTHER PTHR11588 UniProtKB/TrEMBL
  TUBULIN BETA 8B-RELATED UniProtKB/TrEMBL
  TUBULIN BETA-4B CHAIN UniProtKB/TrEMBL
Pfam Tubulin UniProtKB/TrEMBL
  Tubulin_C UniProtKB/TrEMBL
PRINTS BETATUBULIN UniProtKB/TrEMBL
  TUBULIN UniProtKB/TrEMBL
PROSITE TUBULIN UniProtKB/TrEMBL
  TUBULIN_B_AUTOREG UniProtKB/TrEMBL
SMART Tubulin UniProtKB/TrEMBL
  Tubulin_C UniProtKB/TrEMBL
Superfamily-SCOP SSF52490 UniProtKB/TrEMBL
  SSF55307 UniProtKB/TrEMBL
UniProt A0A2R9AK70_PANPA UniProtKB/TrEMBL
  A0A2R9APU8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9APV8_PANPA UniProtKB/TrEMBL
  A0A2R9B2G9 ENTREZGENE, UniProtKB/TrEMBL