CUL7 (cullin 7) - Rat Genome Database

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Gene: CUL7 (cullin 7) Pan paniscus
Analyze
Symbol: CUL7
Name: cullin 7
RGD ID: 11870787
Description: ENCODES a protein that exhibits ubiquitin ligase complex scaffold activity (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN Golgi organization (ortholog); PARTICIPATES IN neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; ASSOCIATED WITH 3-M syndrome (ortholog); autistic disorder (ortholog); Dwarfism (ortholog); FOUND IN 3M complex (inferred); centrosome (inferred); Cul7-RING ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cullin-7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,537,771 - 57,554,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,408,020 - 53,424,370 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,629,158 - 42,646,279 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,924,337 - 43,941,185 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,924,408 - 43,942,768 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CUL7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,537,771 - 57,554,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,408,020 - 53,424,370 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,629,158 - 42,646,279 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,924,337 - 43,941,185 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,924,408 - 43,942,768 (-)Ensemblpanpan1.1panPan2
CUL7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,037,617 - 43,053,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,037,617 - 43,053,943 (-)EnsemblGRCh38hg38GRCh38
GRCh37643,005,355 - 43,021,589 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,113,333 - 43,129,632 (-)NCBINCBI36Build 36hg18NCBI36
Build 34643,113,333 - 43,129,632NCBI
Celera644,557,598 - 44,573,926 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,722,458 - 42,738,676 (-)NCBIHuRef
CHM1_1643,007,804 - 43,024,128 (-)NCBICHM1_1
T2T-CHM13v2.0642,866,701 - 42,882,922 (-)NCBIT2T-CHM13v2.0
Cul7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,961,264 - 46,975,290 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,961,263 - 46,975,290 (+)EnsemblGRCm39 Ensembl
GRCm381746,650,338 - 46,664,364 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,650,337 - 46,664,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371746,787,287 - 46,801,313 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,113,529 - 46,127,555 (+)NCBIMGSCv36mm8
Celera1750,086,221 - 50,100,235 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Cul7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,816,703 - 21,830,344 (-)NCBIGRCr8
mRatBN7.2914,319,102 - 14,333,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,319,108 - 14,332,741 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0916,629,491 - 16,643,527 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,629,401 - 16,643,182 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,536,106 - 15,549,905 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,020,543 - 10,034,167 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera912,066,970 - 12,080,701 (-)NCBICelera
Cytogenetic Map9q12NCBI
Cul7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,003,533 - 9,017,281 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,003,482 - 9,018,260 (-)NCBIChiLan1.0ChiLan1.0
CUL7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,559,637 - 11,574,320 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,559,667 - 11,575,023 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,586,654 - 11,601,312 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,041,004 - 12,055,659 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,041,006 - 12,055,810 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,569,636 - 11,584,293 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,653,702 - 11,668,357 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,747,764 - 11,762,421 (-)NCBIUU_Cfam_GSD_1.0
Cul7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,058,670 - 47,073,781 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,887,610 - 16,901,458 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,886,416 - 16,901,532 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUL7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,097,854 - 38,115,822 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,097,848 - 38,116,041 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,546,218 - 43,559,813 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUL7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,106,413 - 29,124,408 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,105,004 - 29,123,565 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,099,333 - 43,116,525 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cul7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,459,134 - 16,472,675 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,454,304 - 16,472,721 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000047634   ⟹   ENSPPAP00000024808
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,924,408 - 43,942,768 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000047643   ⟹   ENSPPAP00000024817
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,924,408 - 43,942,379 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000047652   ⟹   ENSPPAP00000024826
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,924,408 - 43,940,021 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000047653   ⟹   ENSPPAP00000024827
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl643,924,408 - 43,940,021 (-)Ensembl
RefSeq Acc Id: XM_003833271   ⟹   XP_003833319
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,537,771 - 57,554,113 (-)NCBI
NHGRI_mPanPan1653,408,020 - 53,424,370 (-)NCBI
Mhudiblu_PPA_v0642,629,158 - 42,646,279 (-)NCBI
PanPan1.1643,924,337 - 43,941,174 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008958772   ⟹   XP_008957020
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,537,771 - 57,554,113 (-)NCBI
NHGRI_mPanPan1653,408,020 - 53,424,370 (-)NCBI
Mhudiblu_PPA_v0642,629,158 - 42,646,278 (-)NCBI
PanPan1.1643,924,337 - 43,941,128 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034962114   ⟹   XP_034818005
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2557,537,771 - 57,553,976 (-)NCBI
NHGRI_mPanPan1653,408,020 - 53,424,232 (-)NCBI
Mhudiblu_PPA_v0642,629,158 - 42,646,126 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003833319 (Get FASTA)   NCBI Sequence Viewer  
  XP_008957020 (Get FASTA)   NCBI Sequence Viewer  
  XP_034818005 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024808.1
  ENSPPAP00000024817.1
  ENSPPAP00000024826.1
  ENSPPAP00000024827.1
RefSeq Acc Id: XP_003833319   ⟸   XM_003833271
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B5F0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008957020   ⟸   XM_008958772
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B5F0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034818005   ⟸   XM_034962114
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B5F0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000024808   ⟸   ENSPPAT00000047634
Ensembl Acc Id: ENSPPAP00000024817   ⟸   ENSPPAT00000047643
Ensembl Acc Id: ENSPPAP00000024826   ⟸   ENSPPAT00000047652
Ensembl Acc Id: ENSPPAP00000024827   ⟸   ENSPPAT00000047653
Protein Domains
Cullin family profile   DOC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035495 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047634.1 UniProtKB/TrEMBL
  ENSPPAT00000047643.1 UniProtKB/TrEMBL
  ENSPPAT00000047652.1 UniProtKB/TrEMBL
  ENSPPAT00000047653.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  2.30.30.30 UniProtKB/TrEMBL
  Cullin Repeats UniProtKB/TrEMBL
  Cullin, Chain C, Domain 2 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
InterPro APC_su10/DOC_dom UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CPH_domain UniProtKB/TrEMBL
  Cullin UniProtKB/TrEMBL
  Cullin_homology UniProtKB/TrEMBL
  Cullin_homology_sf UniProtKB/TrEMBL
  Cullin_N UniProtKB/TrEMBL
  Cullin_neddylation_domain UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Rib_L2_dom2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene CUL7 ENTREZGENE
PANTHER CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING UniProtKB/TrEMBL
  PTHR22771:SF3 UniProtKB/TrEMBL
Pfam ANAPC10 UniProtKB/TrEMBL
  Cul7 UniProtKB/TrEMBL
  Cullin UniProtKB/TrEMBL
PROSITE CULLIN_2 UniProtKB/TrEMBL
  DOC UniProtKB/TrEMBL
SMART APC10 UniProtKB/TrEMBL
  Cullin_Nedd8 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  SSF75632 UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0A2R9B5F0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B5G0_PANPA UniProtKB/TrEMBL
  A0A2R9B6Y8_PANPA UniProtKB/TrEMBL