DDX25 (DEAD-box helicase 25) - Rat Genome Database

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Gene: DDX25 (DEAD-box helicase 25) Pan paniscus
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Symbol: DDX25
Name: DEAD-box helicase 25
RGD ID: 11863089
Description: ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); RNA binding (ortholog); RNA helicase activity (ortholog); INVOLVED IN mRNA export from nucleus (inferred); regulation of translation (inferred); spermatid development (inferred); ASSOCIATED WITH azoospermia (ortholog); chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); FOUND IN chromatoid body (inferred); cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DDX25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,587,696 - 126,607,452 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111127,695,274 - 127,715,018 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011120,718,758 - 120,738,527 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,632,841 - 124,651,525 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,632,841 - 124,667,585 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatoid body  (IEA)
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DDX25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,587,696 - 126,607,452 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111127,695,274 - 127,715,018 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011120,718,758 - 120,738,527 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,632,841 - 124,651,525 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,632,841 - 124,667,585 (+)Ensemblpanpan1.1panPan2
DDX25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,903,328 - 125,928,843 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,903,348 - 125,943,702 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,773,223 - 125,798,738 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611125,279,613 - 125,298,215 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411125,279,612 - 125,298,213NCBI
Celera11122,934,293 - 122,953,028 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11121,716,218 - 121,734,969 (+)NCBIHuRef
CHM1_111125,661,010 - 125,679,757 (+)NCBICHM1_1
T2T-CHM13v2.011125,932,197 - 125,957,695 (+)NCBIT2T-CHM13v2.0
Ddx25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39935,453,144 - 35,469,766 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl935,447,943 - 35,469,824 (-)EnsemblGRCm39 Ensembl
GRCm38935,541,848 - 35,558,470 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl935,536,647 - 35,558,528 (-)EnsemblGRCm38mm10GRCm38
MGSCv37935,349,433 - 35,366,055 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36935,291,496 - 35,308,135 (-)NCBIMGSCv36mm8
Celera932,778,916 - 32,795,591 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.31NCBI
Ddx25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8842,152,046 - 42,168,635 (-)NCBIGRCr8
mRatBN7.2833,894,224 - 33,910,377 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl833,894,232 - 33,921,764 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx837,970,852 - 37,986,873 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0836,253,902 - 36,269,922 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0834,116,733 - 34,132,752 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0836,744,686 - 36,760,720 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,744,667 - 36,760,742 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0836,761,172 - 36,777,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4835,326,939 - 35,342,973 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1835,335,705 - 35,351,739 (-)NCBI
Celera835,315,323 - 35,331,357 (-)NCBICelera
Cytogenetic Map8q21NCBI
Ddx25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,952,239 - 26,972,100 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,952,655 - 26,973,758 (+)NCBIChiLan1.0ChiLan1.0
DDX25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,566,748 - 8,585,965 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,566,754 - 8,586,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,627,271 - 8,647,444 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,523,128 - 8,543,524 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,523,136 - 8,543,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,591,262 - 8,611,439 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,565,502 - 8,585,675 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,599,553 - 8,619,741 (-)NCBIUU_Cfam_GSD_1.0
Ddx25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947108,128,868 - 108,149,009 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365726,301,347 - 6,321,542 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365726,301,347 - 6,322,640 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl953,029,790 - 53,044,383 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1953,029,450 - 53,044,088 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,760,963 - 58,772,124 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11117,035,171 - 117,053,726 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1117,035,310 - 117,053,494 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,017,831 - 9,037,268 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481252,368 - 74,149 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462481253,129 - 74,073 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000030560   ⟹   ENSPPAP00000007937
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11124,632,841 - 124,651,525 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000030562   ⟹   ENSPPAP00000007939
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11124,636,680 - 124,667,585 (+)Ensembl
RefSeq Acc Id: XM_003819902   ⟹   XP_003819950
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29126,588,560 - 126,607,452 (+)NCBI
NHGRI_mPanPan111127,696,134 - 127,715,018 (+)NCBI
Mhudiblu_PPA_v011120,719,857 - 120,738,527 (+)NCBI
PanPan1.111124,632,841 - 124,651,525 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933997   ⟹   XP_034789888
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29126,588,560 - 126,607,452 (+)NCBI
NHGRI_mPanPan111127,696,134 - 127,715,018 (+)NCBI
Mhudiblu_PPA_v011120,719,847 - 120,738,233 (+)NCBI
RefSeq Acc Id: XM_034933998   ⟹   XP_034789889
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29126,587,696 - 126,607,452 (+)NCBI
NHGRI_mPanPan111127,695,274 - 127,715,018 (+)NCBI
Mhudiblu_PPA_v011120,718,758 - 120,738,527 (+)NCBI
RefSeq Acc Id: XM_055095052   ⟹   XP_054951027
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29126,588,931 - 126,607,452 (+)NCBI
NHGRI_mPanPan111127,696,509 - 127,715,018 (+)NCBI
RefSeq Acc Id: XM_055095053   ⟹   XP_054951028
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29126,588,977 - 126,607,452 (+)NCBI
NHGRI_mPanPan111127,696,555 - 127,715,018 (+)NCBI
RefSeq Acc Id: XM_055095055   ⟹   XP_054951030
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29126,587,815 - 126,607,452 (+)NCBI
NHGRI_mPanPan111127,695,393 - 127,715,018 (+)NCBI
RefSeq Acc Id: XP_003819950   ⟸   XM_003819902
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZYC3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789889   ⟸   XM_034933998
- Peptide Label: isoform X5
RefSeq Acc Id: XP_034789888   ⟸   XM_034933997
- Peptide Label: isoform X2
Ensembl Acc Id: ENSPPAP00000007939   ⟸   ENSPPAT00000030562
Ensembl Acc Id: ENSPPAP00000007937   ⟸   ENSPPAT00000030560
RefSeq Acc Id: XP_054951030   ⟸   XM_055095055
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054951027   ⟸   XM_055095052
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054951028   ⟸   XM_055095053
- Peptide Label: isoform X4
Protein Domains
DEAD-box RNA helicase Q   Helicase ATP-binding   Helicase C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027196 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030560.1 UniProtKB/TrEMBL
  ENSPPAT00000030562.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  6.10.250.2170 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
KEGG Report pps:100979042 UniProtKB/TrEMBL
NCBI Gene DDX25 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBP3 UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DDX25 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZSJ4_PANPA UniProtKB/TrEMBL
  A0A2R8ZYC3 ENTREZGENE, UniProtKB/TrEMBL