DEFB115 (defensin beta 115) - Rat Genome Database

Name: DEFB115
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: DEFB115 (defensin beta 115) Pan paniscus

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Symbol:

DEFB115

Name:

defensin beta 115

RGD ID:

11858374

Description:

INVOLVED IN defense response to bacterium (inferred); defense response to Gram-negative bacterium (inferred); innate immune response (inferred); FOUND IN extracellular region (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

beta-defensin 115

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DEFB115 (defensin beta 115)	NCBI	Ortholog
Mus musculus (house mouse):	Defb28 (defensin beta 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Defb28 (defensin beta 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Defb115 (defensin beta 115)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Defb115 (defensin beta 115)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DEFB115 (defensin beta 115)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DEFB115 (defensin beta 115)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	36,951,250 - 36,953,221 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	36,944,347 - 36,946,318 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	27,549,214 - 27,551,185 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	28,185,796 - 28,187,767 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	28,185,796 - 28,187,767 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to bacterium (IEA)

defense response to Gram-negative bacterium (IEA)

innate immune response (IEA)

Cellular Component

extracellular region (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

DEFB115
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	36,951,250 - 36,953,221 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	36,944,347 - 36,946,318 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	27,549,214 - 27,551,185 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	28,185,796 - 28,187,767 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	28,185,796 - 28,187,767 (+)	Ensembl	panpan1.1		panPan2

DEFB115
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	31,257,664 - 31,259,632 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	31,257,664 - 31,259,632 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	29,845,467 - 29,847,435 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	29,309,128 - 29,311,096 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	26,601,734 - 26,603,702 (+)	NCBI		Celera
Cytogenetic Map	20	q11.21	NCBI
HuRef	20	26,634,234 - 26,636,202 (+)	NCBI		HuRef
CHM1_1	20	29,749,417 - 29,751,385 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	32,981,800 - 32,983,768 (+)	NCBI		T2T-CHM13v2.0

Defb28
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	152,360,175 - 152,363,367 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	152,360,175 - 152,363,367 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	152,518,255 - 152,521,447 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	152,518,255 - 152,521,447 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	152,343,991 - 152,347,183 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	152,209,696 - 152,212,888 (+)	NCBI		MGSCv36	mm8
Celera	2	158,333,666 - 158,336,858 (+)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	75.2	NCBI

Defb28
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	161,448,316 - 161,454,051 (+)	NCBI		GRCr8
mRatBN7.2	3	140,988,032 - 140,993,767 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	140,988,032 - 140,991,015 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	147,992,754 - 147,995,911 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	147,992,754 - 147,994,616 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	154,337,607 - 154,340,662 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	142,838,348 - 142,853,944 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	139,738,883 - 139,742,040 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

Defb115
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955422	29,676,981 - 29,681,067 (+)	NCBI	ChiLan1.0	ChiLan1.0

Defb115
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	169,896,285 - 169,900,610 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936485	18,327,656 - 18,347,183 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DEFB115
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	35,028,972 - 35,031,088 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	35,029,031 - 35,034,148 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	39,835,623 - 39,840,655 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DEFB115
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	2	35,689,783 - 35,691,760 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	91,265,351 - 91,267,501 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003833413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057300878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000030699 ⟹ ENSPPAP00000008064

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	20	28,185,796 - 28,187,767 (+)	Ensembl

RefSeq Acc Id:

XM_057300878 ⟹ XP_057156861

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	21	36,951,250 - 36,953,221 (+)	NCBI
NHGRI_mPanPan1	20	36,944,347 - 36,946,318 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_057156861	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000008064.1

Ensembl Acc Id:

ENSPPAP00000008064 ⟸ ENSPPAT00000030699

RefSeq Acc Id:	XP_057156861 ⟸ XM_057300878
- UniProtKB:	A0A2R8ZSX3 (UniProtKB/TrEMBL)

Protein Domains

Beta-defensin

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000027269	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000030699.1	UniProtKB/TrEMBL
InterPro	Beta-defensin	UniProtKB/TrEMBL
	Beta_defensin	UniProtKB/TrEMBL
KEGG Report	pps:100970433	UniProtKB/TrEMBL
NCBI Gene	DEFB115	ENTREZGENE
PANTHER	BETA-DEFENSIN 115	UniProtKB/TrEMBL
	BETA-DEFENSIN 123-RELATED	UniProtKB/TrEMBL
Pfam	Defensin_beta_2	UniProtKB/TrEMBL
UniProt	A0A2R8ZSX3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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