PGGHG (protein-glucosylgalactosylhydroxylysine glucosidase) - Rat Genome Database

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Gene: PGGHG (protein-glucosylgalactosylhydroxylysine glucosidase) Pan paniscus
Analyze
Symbol: PGGHG
Name: protein-glucosylgalactosylhydroxylysine glucosidase
RGD ID: 11849133
Description: ENCODES a protein that exhibits alpha,alpha-trehalase activity (inferred); catalytic activity (inferred); protein-glucosylgalactosylhydroxylysine glucosidase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); trehalose catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 39 (ortholog); osteogenesis imperfecta (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acid trehalase-like protein 1; LOC117978578; protein-glucosylgalactosylhydroxylysine glucosidase-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,657,159 - 2,664,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1111,813,099 - 1,819,428 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011284,672 - 291,814 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111329,289 - 335,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11329,289 - 335,856 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PGGHG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,657,159 - 2,664,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1111,813,099 - 1,819,428 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011284,672 - 291,814 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111329,289 - 335,856 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11329,289 - 335,856 (+)Ensemblpanpan1.1panPan2
PGGHG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811289,126 - 296,107 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11289,126 - 296,107 (+)EnsemblGRCh38hg38GRCh38
GRCh3711289,126 - 296,107 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611280,694 - 285,412 (+)NCBINCBI36Build 36hg18NCBI36
Celera11263,762 - 270,317 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11108,765 - 115,218 (+)NCBIHuRef
CHM1_111288,068 - 294,653 (+)NCBICHM1_1
T2T-CHM13v2.011328,918 - 337,324 (+)NCBIT2T-CHM13v2.0
Pgghg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,521,304 - 140,527,577 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,521,304 - 140,527,577 (+)EnsemblGRCm39 Ensembl
GRCm387140,941,391 - 140,947,664 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7140,941,391 - 140,947,664 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,127,480 - 148,133,557 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367140,792,901 - 140,798,978 (+)NCBIMGSCv36mm8
Celera7140,733,989 - 140,740,066 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.16NCBI
Pgghg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,467,179 - 205,474,185 (+)NCBIGRCr8
mRatBN7.21196,038,276 - 196,044,561 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,039,103 - 196,044,372 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01213,734,198 - 213,743,233 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,737,788 - 213,742,637 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,658,372 - 220,664,399 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,121,951 - 201,126,577 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11201,271,942 - 201,276,569 (+)NCBI
Celera1193,672,165 - 193,678,717 (+)NCBICelera
Cytogenetic Map1q41NCBI
Pgghg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,749,483 - 11,754,118 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,749,483 - 11,754,008 (-)NCBIChiLan1.0ChiLan1.0
PGGHG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,443,387 - 25,449,288 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,443,387 - 25,449,405 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,093,049 - 25,099,033 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01825,970,263 - 25,976,255 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1825,970,207 - 25,976,247 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,538,083 - 25,544,069 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,182,855 - 25,188,838 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01825,795,352 - 25,801,335 (+)NCBIUU_Cfam_GSD_1.0
Pgghg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947152,843 - 158,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888152,873 - 158,560 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888152,919 - 158,549 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGGHG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl299,271 - 106,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1299,254 - 104,898 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22162,118,090 - 162,125,427 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PGGHG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11102,388 - 109,337 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1102,136 - 108,370 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,142,151 - 97,148,794 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgghg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476622,137,533 - 22,141,975 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476622,136,826 - 22,142,218 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000035718   ⟹   ENSPPAP00000013050
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11329,289 - 335,856 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000035726   ⟹   ENSPPAP00000013058
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11330,692 - 334,739 (+)Ensembl
RefSeq Acc Id: XM_034931786   ⟹   XP_034787677
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,657,164 - 2,664,455 (+)NCBI
NHGRI_mPanPan1111,813,104 - 1,819,428 (+)NCBI
Mhudiblu_PPA_v011284,693 - 291,814 (+)NCBI
RefSeq Acc Id: XM_034931787   ⟹   XP_034787678
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,657,177 - 2,664,455 (+)NCBI
NHGRI_mPanPan1111,813,114 - 1,819,428 (+)NCBI
Mhudiblu_PPA_v011284,706 - 291,814 (+)NCBI
RefSeq Acc Id: XM_034931789   ⟹   XP_034787680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,657,159 - 2,664,455 (+)NCBI
NHGRI_mPanPan1111,813,099 - 1,819,428 (+)NCBI
Mhudiblu_PPA_v011284,672 - 291,814 (+)NCBI
RefSeq Acc Id: XM_034931791   ⟹   XP_034787682
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,657,172 - 2,664,455 (+)NCBI
NHGRI_mPanPan1111,813,112 - 1,819,428 (+)NCBI
Mhudiblu_PPA_v011284,683 - 291,814 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034787677 (Get FASTA)   NCBI Sequence Viewer  
  XP_034787678 (Get FASTA)   NCBI Sequence Viewer  
  XP_034787680 (Get FASTA)   NCBI Sequence Viewer  
  XP_034787682 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013050.1
  ENSPPAP00000013058.1
Reference Protein Sequences
RefSeq Acc Id: XP_034787680   ⟸   XM_034931789
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034787682   ⟸   XM_034931791
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034787677   ⟸   XM_034931786
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034787678   ⟸   XM_034931787
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000013058   ⟸   ENSPPAT00000035726
RefSeq Acc Id: ENSPPAP00000013050   ⟸   ENSPPAT00000035718
Protein Domains
Glycoside hydrolase family 65 central catalytic


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029687 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035718.1 UniProtKB/TrEMBL
  ENSPPAT00000035726.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/TrEMBL
  Maltose phosphorylase, domain 3 UniProtKB/TrEMBL
InterPro 6-hairpin_glycosidase_sf UniProtKB/TrEMBL
  6hp_glycosidase-like_sf UniProtKB/TrEMBL
  Glyco_hydro_65_M UniProtKB/TrEMBL
NCBI Gene PGGHG ENTREZGENE
PANTHER GLYCOSYL HYDROLASE-RELATED UniProtKB/TrEMBL
  PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE UniProtKB/TrEMBL
Pfam Glyco_hydro_65m UniProtKB/TrEMBL
Superfamily-SCOP SSF48208 UniProtKB/TrEMBL
UniProt A0A2R9A6Z2_PANPA UniProtKB/TrEMBL
  A0A2R9A832_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 PGGHG  protein-glucosylgalactosylhydroxylysine glucosidase  LOC117978578  protein-glucosylgalactosylhydroxylysine glucosidase-like  Data merged from RGD:32726559 737654 PROVISIONAL