NME3 (NME/NM23 nucleoside diphosphate kinase 3) - Rat Genome Database

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Gene: NME3 (NME/NM23 nucleoside diphosphate kinase 3) Pan paniscus
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Symbol: NME3
Name: NME/NM23 nucleoside diphosphate kinase 3
RGD ID: 11791320
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleoside diphosphate kinase activity (inferred); INVOLVED IN CTP biosynthetic process (inferred); DNA repair (inferred); GTP biosynthetic process (inferred); PARTICIPATES IN de novo pyrimidine biosynthetic pathway; ASSOCIATED WITH epilepsy (ortholog); idiopathic generalized epilepsy (ortholog); short-rib thoracic dysplasia 9 with or without polydactyly (ortholog); FOUND IN cell projection (inferred); ciliary basal body (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleoside diphosphate kinase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,036,976 - 2,038,428 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,818,421 - 5,819,857 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016392,694 - 394,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,822,719 - 1,824,160 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,822,719 - 1,824,147 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NME3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,036,976 - 2,038,428 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,818,421 - 5,819,857 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016392,694 - 394,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,822,719 - 1,824,160 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,822,719 - 1,824,147 (-)Ensemblpanpan1.1panPan2
NME3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,770,320 - 1,771,543 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,770,320 - 1,771,561 (-)EnsemblGRCh38hg38GRCh38
GRCh37161,820,321 - 1,821,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,760,322 - 1,761,711 (-)NCBINCBI36Build 36hg18NCBI36
Build 34161,760,322 - 1,761,711NCBI
Celera162,032,596 - 2,033,985 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,743,213 - 1,744,602 (-)NCBIHuRef
CHM1_1161,820,269 - 1,821,658 (-)NCBICHM1_1
T2T-CHM13v2.0161,786,150 - 1,787,373 (-)NCBIT2T-CHM13v2.0
Nme3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,115,474 - 25,116,505 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,115,474 - 25,116,496 (+)EnsemblGRCm39 Ensembl
GRCm381724,896,500 - 24,897,531 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,896,500 - 24,897,522 (+)EnsemblGRCm38mm10GRCm38
MGSCv371725,033,445 - 25,034,476 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,624,106 - 24,625,103 (+)NCBIMGSCv36mm8
Celera1725,423,190 - 25,424,231 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Nme3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,421,922 - 14,422,878 (+)NCBIGRCr8
mRatBN7.21013,917,309 - 13,918,415 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,917,403 - 13,918,359 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,664,513 - 18,665,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,153,373 - 18,154,329 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,652,590 - 13,653,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,258,232 - 14,259,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,258,380 - 14,259,336 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,074,396 - 14,075,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,145,488 - 14,146,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11014,145,487 - 14,146,444 (+)NCBI
Celera1013,596,611 - 13,597,567 (+)NCBICelera
Cytogenetic Map10q12NCBI
Nme3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,497,779 - 15,498,873 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,497,779 - 15,498,873 (+)NCBIChiLan1.0ChiLan1.0
NME3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,131,807 - 39,132,756 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,370,445 - 40,371,394 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,447,987 - 39,448,936 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1639,124,673 - 39,125,622 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,097,254 - 39,098,202 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,575,702 - 39,576,651 (+)NCBIUU_Cfam_GSD_1.0
Nme3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,486,486 - 104,487,636 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,221,915 - 2,222,814 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,222,055 - 2,222,977 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NME3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,195,635 - 40,196,869 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,195,456 - 40,197,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,659,552 - 41,661,739 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NME3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,679,361 - 1,680,796 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,679,549 - 1,680,547 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,405,487 - 29,406,892 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nme3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913480,190 - 481,023 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913479,893 - 481,023 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000036504   ⟹   ENSPPAP00000013830
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl161,822,719 - 1,824,147 (-)Ensembl
RefSeq Acc Id: XM_003807609   ⟹   XP_003807657
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,036,976 - 2,038,428 (-)NCBI
NHGRI_mPanPan1165,818,421 - 5,819,857 (-)NCBI
Mhudiblu_PPA_v016392,694 - 394,076 (-)NCBI
PanPan1.1161,822,719 - 1,824,148 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959748   ⟹   XP_008957996
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,036,976 - 2,038,367 (-)NCBI
NHGRI_mPanPan1165,818,421 - 5,819,793 (-)NCBI
Mhudiblu_PPA_v016392,714 - 394,095 (-)NCBI
PanPan1.1161,822,719 - 1,824,155 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959749   ⟹   XP_008957997
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,036,976 - 2,038,353 (-)NCBI
NHGRI_mPanPan1165,818,421 - 5,819,806 (-)NCBI
Mhudiblu_PPA_v016392,714 - 394,106 (-)NCBI
PanPan1.1161,822,719 - 1,824,160 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055100717   ⟹   XP_054956692
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,036,976 - 2,038,353 (-)NCBI
NHGRI_mPanPan1165,818,421 - 5,819,794 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003807657 (Get FASTA)   NCBI Sequence Viewer  
  XP_008957996 (Get FASTA)   NCBI Sequence Viewer  
  XP_008957997 (Get FASTA)   NCBI Sequence Viewer  
  XP_054956692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013830
  ENSPPAP00000013830.1
RefSeq Acc Id: XP_008957997   ⟸   XM_008959749
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008957996   ⟸   XM_008959748
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003807657   ⟸   XM_003807609
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A983 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000013830   ⟸   ENSPPAT00000036504
RefSeq Acc Id: XP_054956692   ⟸   XM_055100717
- Peptide Label: isoform X4
Protein Domains
Nucleoside diphosphate kinase-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036504.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.141 UniProtKB/TrEMBL
InterPro NDK-like_dom UniProtKB/TrEMBL
  NDK-like_dom_sf UniProtKB/TrEMBL
  Nucleoside_diP_kinase UniProtKB/TrEMBL
  Nucleoside_diP_kinase_AS UniProtKB/TrEMBL
KEGG Report pps:100985482 UniProtKB/TrEMBL
NCBI Gene NME3 ENTREZGENE
PANTHER NUCLEOSIDE DIPHOSPHATE KINASE UniProtKB/TrEMBL
  NUCLEOSIDE DIPHOSPHATE KINASE 3 UniProtKB/TrEMBL
Pfam NDK UniProtKB/TrEMBL
PRINTS NUCDPKINASE UniProtKB/TrEMBL
PROSITE NDP_KINASES UniProtKB/TrEMBL
SMART NDK UniProtKB/TrEMBL
Superfamily-SCOP SSF54919 UniProtKB/TrEMBL
UniProt A0A2R9A983 ENTREZGENE, UniProtKB/TrEMBL