PRSS54 (serine protease 54) - Rat Genome Database

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Gene: PRSS54 (serine protease 54) Pan paniscus
Analyze
Symbol: PRSS54
Name: serine protease 54
RGD ID: 11731873
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); developmental and epileptic encephalopathy (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive serine protease 54; protease, serine 54
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,743,145 - 67,758,203 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,663,994 - 73,679,041 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,548,915 - 38,562,629 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,678,790 - 57,693,680 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,678,790 - 57,693,680 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PRSS54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,743,145 - 67,758,203 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,663,994 - 73,679,041 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,548,915 - 38,562,629 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,678,790 - 57,693,680 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,678,790 - 57,693,680 (-)Ensemblpanpan1.1panPan2
PRSS54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,279,997 - 58,295,025 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1658,279,997 - 58,295,047 (-)EnsemblGRCh38hg38GRCh38
GRCh371658,313,901 - 58,328,929 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,871,402 - 56,886,452 (-)NCBINCBI36Build 36hg18NCBI36
Celera1642,813,348 - 42,828,405 (-)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1644,182,249 - 44,197,306 (-)NCBIHuRef
CHM1_11659,720,789 - 59,735,855 (-)NCBICHM1_1
T2T-CHM13v2.01664,075,287 - 64,090,313 (-)NCBIT2T-CHM13v2.0
Prss54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39896,285,694 - 96,302,965 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl896,285,697 - 96,302,968 (-)EnsemblGRCm39 Ensembl
GRCm38895,559,066 - 95,576,337 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,559,069 - 95,576,340 (-)EnsemblGRCm38mm10GRCm38
MGSCv37898,083,192 - 98,099,097 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36898,448,199 - 98,464,326 (-)NCBIMGSCv36mm8
MGSCv36895,358,238 - 95,373,984 (-)NCBIMGSCv36mm8
Celera899,870,836 - 99,886,555 (-)NCBICelera
Cytogenetic Map8D1NCBI
cM Map847.12NCBI
Prss54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,486,059 - 9,502,900 (+)NCBIGRCr8
mRatBN7.2199,479,995 - 9,496,838 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,479,995 - 9,496,835 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,448,242 - 9,465,133 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,215,068 - 10,231,959 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,501,391 - 9,518,286 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,895,052 - 9,911,965 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,895,121 - 9,911,959 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,880,069 - 9,896,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,938,003 - 9,954,844 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,942,828 - 9,959,667 (+)NCBI
Celera199,373,558 - 9,390,626 (+)NCBICelera
Cytogenetic Map19p13NCBI
Prss54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,775,880 - 15,788,524 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,775,492 - 15,788,128 (-)NCBIChiLan1.0ChiLan1.0
PRSS54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,318,971 - 58,332,056 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,318,150 - 58,332,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,948,931 - 54,962,014 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0258,857,437 - 58,870,494 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl258,731,660 - 58,870,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1255,687,278 - 55,700,373 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0256,694,864 - 56,707,967 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0257,589,406 - 57,602,491 (+)NCBIUU_Cfam_GSD_1.0
Prss54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,442,421 - 49,453,028 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647510,136,275 - 10,146,626 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647510,136,275 - 10,146,654 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRSS54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl620,083,221 - 20,100,786 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1620,085,494 - 20,090,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2618,144,197 - 18,161,503 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRSS54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1544,214,986 - 44,249,005 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl544,215,216 - 44,229,224 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604731,949,429 - 31,962,389 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prss54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474627,942,210 - 27,954,698 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474627,952,022 - 27,954,879 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000056748   ⟹   ENSPPAP00000033869
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1657,678,790 - 57,693,680 (-)Ensembl
RefSeq Acc Id: XM_055099172   ⟹   XP_054955147
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,743,145 - 67,758,197 (-)NCBI
NHGRI_mPanPan11673,663,994 - 73,679,035 (-)NCBI
RefSeq Acc Id: XM_055099173   ⟹   XP_054955148
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21867,743,147 - 67,758,203 (-)NCBI
NHGRI_mPanPan11673,663,996 - 73,679,041 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054955147 (Get FASTA)   NCBI Sequence Viewer  
  XP_054955148 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000033869.1
Ensembl Acc Id: ENSPPAP00000033869   ⟸   ENSPPAT00000056748
RefSeq Acc Id: XP_054955147   ⟸   XM_055099172
- UniProtKB: A0A2R9C5Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054955148   ⟸   XM_055099173
- UniProtKB: A0A2R9C5Q3 (UniProtKB/TrEMBL)
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039795 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056748.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
NCBI Gene PRSS54 ENTREZGENE
PANTHER CHYMOTRYPSIN-RELATED UniProtKB/TrEMBL
  INACTIVE SERINE PROTEASE 54 UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A2R9C5Q3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-23 PRSS54  serine protease 54    protease, serine 54  Symbol and/or name change 5135510 APPROVED