PKP4 (plakophilin 4) - Rat Genome Database

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Gene: PKP4 (plakophilin 4) Pan paniscus
Analyze
Symbol: PKP4
Name: plakophilin 4
RGD ID: 11721877
Description: INVOLVED IN positive regulation of GTPase activity (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN adherens junction (inferred); anchoring junction (inferred); cell junction (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plakophilin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21361,132,065 - 61,359,242 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B61,147,039 - 61,374,216 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B45,726,315 - 45,953,602 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B162,965,884 - 163,192,565 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B162,986,256 - 163,192,565 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PKP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21361,132,065 - 61,359,242 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B61,147,039 - 61,374,216 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B45,726,315 - 45,953,602 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B162,965,884 - 163,192,565 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B162,986,256 - 163,192,565 (+)Ensemblpanpan1.1panPan2
PKP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382158,456,952 - 158,681,429 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2158,456,952 - 158,682,879 (+)EnsemblGRCh38hg38GRCh38
GRCh372159,313,464 - 159,537,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362159,021,722 - 159,246,187 (+)NCBINCBI36Build 36hg18NCBI36
Build 342159,138,983 - 159,363,445NCBI
Celera2152,930,251 - 153,154,736 (+)NCBICelera
Cytogenetic Map2q24.1NCBI
HuRef2151,277,855 - 151,426,157 (+)NCBIHuRef
CHM1_12159,319,662 - 159,544,088 (+)NCBICHM1_1
T2T-CHM13v2.02158,913,757 - 159,138,252 (+)NCBIT2T-CHM13v2.0
Pkp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39258,991,123 - 59,185,549 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl258,991,194 - 59,185,552 (+)EnsemblGRCm39 Ensembl
GRCm38259,160,850 - 59,355,205 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl259,160,850 - 59,355,208 (+)EnsemblGRCm38mm10GRCm38
MGSCv37258,998,907 - 59,193,262 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36258,961,859 - 59,156,042 (+)NCBIMGSCv36mm8
Celera260,907,299 - 61,046,531 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map233.52NCBI
Pkp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8364,040,995 - 64,244,586 (+)NCBIGRCr8
mRatBN7.2343,632,364 - 43,835,834 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl343,631,880 - 43,835,474 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0345,211,097 - 45,414,524 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl345,277,348 - 45,414,613 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0350,328,374 - 50,531,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4340,859,032 - 41,062,477 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1340,785,055 - 40,958,851 (+)NCBI
Celera341,682,689 - 41,884,590 (+)NCBICelera
Cytogenetic Map3q21NCBI
Pkp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544914,833,945 - 15,051,007 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544914,835,423 - 15,050,237 (-)NCBIChiLan1.0ChiLan1.0
PKP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1364,342,715 - 4,575,672 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl364,342,688 - 4,575,016 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha364,483,224 - 4,715,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0364,465,991 - 4,698,991 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl364,465,724 - 4,698,989 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1364,466,783 - 4,706,254 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0364,526,814 - 4,759,926 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0364,569,772 - 4,802,204 (+)NCBIUU_Cfam_GSD_1.0
Pkp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303121,497,043 - 121,739,971 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646919,875,542 - 20,120,677 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646919,877,749 - 20,120,677 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1565,431,111 - 65,680,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11565,431,173 - 65,680,891 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21572,627,850 - 72,886,964 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PKP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11043,859,446 - 44,089,751 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1043,930,975 - 44,091,291 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040155,487,919 - 155,718,334 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247326,970,728 - 7,208,842 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003832699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008958118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008958121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000050917   ⟹   ENSPPAP00000028073
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B162,986,256 - 163,192,565 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050918   ⟹   ENSPPAP00000028074
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B163,036,235 - 163,192,565 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050920   ⟹   ENSPPAP00000028076
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B163,036,237 - 163,036,524 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050944   ⟹   ENSPPAP00000028100
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B163,036,242 - 163,191,812 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050947   ⟹   ENSPPAP00000028103
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B163,036,242 - 163,088,963 (+)Ensembl
RefSeq Acc Id: XM_034954312   ⟹   XP_034810203
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21361,132,065 - 61,359,242 (+)NCBI
NHGRI_mPanPan12B61,147,039 - 61,374,216 (+)NCBI
Mhudiblu_PPA_v02B45,726,315 - 45,953,602 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034810203 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028073.1
  ENSPPAP00000028074.1
  ENSPPAP00000028076.1
  ENSPPAP00000028100.1
  ENSPPAP00000028103.1
RefSeq Acc Id: XP_034810203   ⟸   XM_034954312
- UniProtKB: A0A2R9BFT5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000028076   ⟸   ENSPPAT00000050920
Ensembl Acc Id: ENSPPAP00000028073   ⟸   ENSPPAT00000050917
Ensembl Acc Id: ENSPPAP00000028074   ⟸   ENSPPAT00000050918
Ensembl Acc Id: ENSPPAP00000028103   ⟸   ENSPPAT00000050947
Ensembl Acc Id: ENSPPAP00000028100   ⟸   ENSPPAT00000050944


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036834 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050917.1 UniProtKB/TrEMBL
  ENSPPAT00000050918.1 UniProtKB/TrEMBL
  ENSPPAT00000050920.1 UniProtKB/TrEMBL
  ENSPPAT00000050944.1 UniProtKB/TrEMBL
  ENSPPAT00000050947.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  Plakophilin/d_Catenin UniProtKB/TrEMBL
NCBI Gene PKP4 ENTREZGENE
PANTHER PTHR10372 UniProtKB/TrEMBL
  PTHR10372:SF8 UniProtKB/TrEMBL
Pfam Arm UniProtKB/TrEMBL
PROSITE ARM_REPEAT UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9BEJ8_PANPA UniProtKB/TrEMBL
  A0A2R9BEM6_PANPA UniProtKB/TrEMBL
  A0A2R9BFT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BFV0_PANPA UniProtKB/TrEMBL
  A0A2R9BN23_PANPA UniProtKB/TrEMBL