RNF180 (ring finger protein 180) - Rat Genome Database

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Gene: RNF180 (ring finger protein 180) Pan paniscus
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Symbol: RNF180
Name: ring finger protein 180
RGD ID: 11714443
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin conjugating enzyme binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN adult behavior (ortholog); norepinephrine metabolic process (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); Triple Negative Breast Neoplasms (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNF180
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2449,538,975 - 49,756,877 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1547,692,604 - 47,913,062 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0549,624,452 - 49,841,741 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1551,279,999 - 51,489,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl551,280,064 - 51,454,750 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNF180
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2449,538,975 - 49,756,877 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1547,692,604 - 47,913,062 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0549,624,452 - 49,841,741 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1551,279,999 - 51,489,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl551,280,064 - 51,454,750 (-)Ensemblpanpan1.1panPan2
RNF180
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38564,165,351 - 64,372,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl564,165,843 - 64,372,869 (+)EnsemblGRCh38hg38GRCh38
GRCh37563,461,670 - 63,668,696 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36563,497,427 - 63,549,369 (+)NCBINCBI36Build 36hg18NCBI36
Build 34563,497,426 - 63,549,369NCBI
Celera560,458,571 - 60,665,603 (+)NCBICelera
Cytogenetic Map5q12.3NCBI
HuRef560,416,366 - 60,622,951 (+)NCBIHuRef
CHM1_1563,461,335 - 63,668,352 (+)NCBICHM1_1
T2T-CHM13v2.0564,985,393 - 65,192,972 (+)NCBIT2T-CHM13v2.0
Rnf180
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913105,267,075 - 105,431,406 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13105,266,509 - 105,431,323 (-)EnsemblGRCm39 Ensembl
GRCm3813105,130,567 - 105,294,818 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13105,130,001 - 105,294,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713105,937,574 - 106,083,094 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613106,250,383 - 106,415,159 (-)NCBIMGSCv36mm8
Celera13109,539,891 - 109,686,561 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.92NCBI
Rnf180
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8238,064,026 - 38,244,854 (-)NCBIGRCr8
mRatBN7.2236,330,285 - 36,511,168 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl236,330,292 - 36,512,614 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx243,445,446 - 43,632,757 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0241,504,097 - 41,691,415 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0236,359,389 - 36,546,713 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0235,718,100 - 35,892,578 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl235,718,889 - 35,870,578 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0254,840,702 - 55,009,539 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4236,186,010 - 36,253,660 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera232,280,890 - 32,455,843 (-)NCBICelera
Cytogenetic Map2q13NCBI
Rnf180
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554464,543,974 - 4,733,569 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554464,544,128 - 4,733,295 (-)NCBIChiLan1.0ChiLan1.0
RNF180
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1250,166,987 - 50,353,694 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl250,197,137 - 50,352,946 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha247,123,982 - 47,310,531 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0250,652,171 - 50,838,819 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl250,583,194 - 50,838,812 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1247,713,305 - 47,899,710 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0248,504,093 - 48,695,296 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0249,398,273 - 49,582,944 (+)NCBIUU_Cfam_GSD_1.0
Rnf180
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213195,722,482 - 195,898,525 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364804,659,751 - 4,834,972 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364804,809,103 - 4,834,977 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF180
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1642,723,065 - 42,953,592 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11642,686,225 - 42,951,928 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21645,753,323 - 46,078,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF180
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1460,340,926 - 60,555,932 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl460,340,804 - 60,557,227 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660498,946,267 - 9,171,918 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf180
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248155,432,991 - 5,622,914 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248155,433,057 - 5,621,833 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000037336   ⟹   ENSPPAP00000014649
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl551,280,064 - 51,454,750 (-)Ensembl
RefSeq Acc Id: XM_008952767   ⟹   XP_008951015
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2449,538,975 - 49,756,877 (-)NCBI
NHGRI_mPanPan1547,692,604 - 47,913,062 (-)NCBI
Mhudiblu_PPA_v0549,624,452 - 49,841,732 (-)NCBI
PanPan1.1551,279,999 - 51,489,588 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034960036   ⟹   XP_034815927
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2449,538,975 - 49,756,821 (-)NCBI
NHGRI_mPanPan1547,692,604 - 47,913,062 (-)NCBI
Mhudiblu_PPA_v0549,624,452 - 49,841,735 (-)NCBI
RefSeq Acc Id: XM_034960038   ⟹   XP_034815929
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2449,538,975 - 49,756,849 (-)NCBI
NHGRI_mPanPan1547,692,604 - 47,913,062 (-)NCBI
Mhudiblu_PPA_v0549,624,452 - 49,841,741 (-)NCBI
RefSeq Acc Id: XM_055112349   ⟹   XP_054968324
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2449,538,975 - 49,756,875 (-)NCBI
NHGRI_mPanPan1547,692,604 - 47,913,062 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008951015 (Get FASTA)   NCBI Sequence Viewer  
  XP_034815927 (Get FASTA)   NCBI Sequence Viewer  
  XP_034815929 (Get FASTA)   NCBI Sequence Viewer  
  XP_054968324 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000014649.1
RefSeq Acc Id: XP_008951015   ⟸   XM_008952767
- Peptide Label: isoform X2
- UniProtKB: A0A2R9ABL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034815929   ⟸   XM_034960038
- Peptide Label: isoform X3
- UniProtKB: A0A2R9ABL1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034815927   ⟸   XM_034960036
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ABL1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000014649   ⟸   ENSPPAT00000037336
RefSeq Acc Id: XP_054968324   ⟸   XM_055112349
- Peptide Label: isoform X4
- UniProtKB: A0A2R9ABL1 (UniProtKB/TrEMBL)
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030487 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000037336.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro RNF180 UniProtKB/TrEMBL
  RNF180_C UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report pps:100975497 UniProtKB/TrEMBL
NCBI Gene RNF180 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF180 UniProtKB/TrEMBL
  PTHR46717 UniProtKB/TrEMBL
Pfam RNF180_C UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A2R9ABL1 ENTREZGENE, UniProtKB/TrEMBL