UBR1 (ubiquitin protein ligase E3 component n-recognin 1) - Rat Genome Database

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Gene: UBR1 (ubiquitin protein ligase E3 component n-recognin 1) Pan paniscus
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Symbol: UBR1
Name: ubiquitin protein ligase E3 component n-recognin 1
RGD ID: 11708578
Description: ENCODES a protein that exhibits L-leucine binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH atherosclerosis (ortholog); Bloom syndrome (ortholog); cardiovascular system disease (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase UBR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21632,190,048 - 32,371,922 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11536,351,852 - 36,533,727 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,899,611 - 22,064,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11540,057,680 - 40,223,042 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1540,060,111 - 40,221,725 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UBR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21632,190,048 - 32,371,922 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11536,351,852 - 36,533,727 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01521,899,611 - 22,064,606 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11540,057,680 - 40,223,042 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1540,060,111 - 40,221,725 (-)Ensemblpanpan1.1panPan2
UBR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381542,942,897 - 43,106,038 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1542,942,897 - 43,106,113 (-)EnsemblGRCh38hg38GRCh38
GRCh371543,235,095 - 43,398,236 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361541,022,387 - 41,185,578 (-)NCBINCBI36Build 36hg18NCBI36
Build 341541,024,818 - 41,185,512NCBI
Celera1520,005,916 - 20,169,100 (-)NCBICelera
Cytogenetic Map15q15.2NCBI
HuRef1520,083,513 - 20,246,655 (-)NCBIHuRef
CHM1_11543,353,443 - 43,517,124 (-)NCBICHM1_1
T2T-CHM13v2.01540,750,009 - 40,913,326 (-)NCBIT2T-CHM13v2.0
Ubr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392120,690,753 - 120,801,246 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2120,690,750 - 120,801,196 (-)EnsemblGRCm39 Ensembl
GRCm382120,860,272 - 120,970,760 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,860,269 - 120,970,715 (-)EnsemblGRCm38mm10GRCm38
MGSCv372120,686,008 - 120,796,451 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362120,553,087 - 120,662,156 (-)NCBIMGSCv36mm8
Celera2121,999,127 - 122,120,067 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.37NCBI
Ubr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83128,265,160 - 128,377,830 (-)NCBIGRCr8
mRatBN7.23107,813,721 - 107,921,701 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,811,392 - 107,922,204 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3111,487,521 - 111,595,462 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03120,083,088 - 120,191,024 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03117,743,477 - 117,851,413 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03112,800,557 - 112,910,038 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3112,800,557 - 112,876,773 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03119,343,521 - 119,453,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,632,668 - 107,746,611 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3106,718,636 - 106,826,666 (-)NCBICelera
Cytogenetic Map3q35NCBI
Ubr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554169,572,171 - 9,731,453 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554169,571,628 - 9,731,551 (-)NCBIChiLan1.0ChiLan1.0
UBR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,869,769 - 10,006,994 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl309,870,021 - 10,006,947 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha309,926,950 - 10,066,799 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03010,005,751 - 10,143,458 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3010,005,841 - 10,143,085 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,920,878 - 10,060,694 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03010,043,912 - 10,181,675 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03010,161,091 - 10,301,368 (-)NCBIUU_Cfam_GSD_1.0
Ubr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864088,324,766 - 88,475,149 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364716,171,593 - 6,313,937 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364716,171,655 - 6,313,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1128,319,311 - 128,474,302 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11128,319,311 - 128,474,330 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21143,202,498 - 143,318,189 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12639,851,630 - 40,026,817 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048100,976,727 - 101,133,413 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480410,036,225 - 10,225,571 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480410,035,122 - 10,225,640 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000029436   ⟹   ENSPPAP00000007253
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1540,060,111 - 40,221,725 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000029446   ⟹   ENSPPAP00000007256
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1540,060,111 - 40,221,725 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000029457   ⟹   ENSPPAP00000007263
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1540,060,111 - 40,221,725 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000029458   ⟹   ENSPPAP00000007264
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1540,204,714 - 40,221,725 (-)Ensembl
RefSeq Acc Id: XM_034938606   ⟹   XP_034794497
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21632,190,048 - 32,371,922 (-)NCBI
NHGRI_mPanPan11536,351,852 - 36,533,727 (-)NCBI
Mhudiblu_PPA_v01521,899,611 - 22,064,605 (-)NCBI
RefSeq Acc Id: XM_055098337   ⟹   XP_054954312
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21632,190,048 - 32,371,900 (-)NCBI
NHGRI_mPanPan11536,351,852 - 36,533,705 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034794497 (Get FASTA)   NCBI Sequence Viewer  
  XP_054954312 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000007253.1
  ENSPPAP00000007256.1
  ENSPPAP00000007263.1
  ENSPPAP00000007264.1
RefSeq Acc Id: XP_034794497   ⟸   XM_034938606
- UniProtKB: A0A2R8ZRU7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000007256   ⟸   ENSPPAT00000029446
Ensembl Acc Id: ENSPPAP00000007253   ⟸   ENSPPAT00000029436
Ensembl Acc Id: ENSPPAP00000007263   ⟸   ENSPPAT00000029457
Ensembl Acc Id: ENSPPAP00000007264   ⟸   ENSPPAT00000029458
RefSeq Acc Id: XP_054954312   ⟸   XM_055098337
- UniProtKB: A0A2R8ZRU7 (UniProtKB/TrEMBL)
Protein Domains
UBR-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026281 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029436.1 UniProtKB/TrEMBL
  ENSPPAT00000029446.1 UniProtKB/TrEMBL
  ENSPPAT00000029457.1 UniProtKB/TrEMBL
  ENSPPAT00000029458.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2670 UniProtKB/TrEMBL
  2.10.110.30 UniProtKB/TrEMBL
  3.30.1390.10 UniProtKB/TrEMBL
InterPro ClpS_core UniProtKB/TrEMBL
  E3_ELL-like UniProtKB/TrEMBL
  E3_ligase_UBR-like_C UniProtKB/TrEMBL
  Ribosomal_L7/12_C/ClpS-like UniProtKB/TrEMBL
  UBR-box_UBR1 UniProtKB/TrEMBL
  UBR1-like UniProtKB/TrEMBL
  UBR1-like_winged-helix UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
  Znf_UBR UniProtKB/TrEMBL
NCBI Gene UBR1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR1 UniProtKB/TrEMBL
  PTHR21497 UniProtKB/TrEMBL
Pfam ClpS UniProtKB/TrEMBL
  PRT6_C UniProtKB/TrEMBL
  UBR1-like_wing UniProtKB/TrEMBL
  zf-UBR UniProtKB/TrEMBL
PROSITE ZF_UBR UniProtKB/TrEMBL
SMART ZnF_UBR1 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF54736 UniProtKB/TrEMBL
UniProt A0A2R8ZQM2_PANPA UniProtKB/TrEMBL
  A0A2R8ZRU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZRV7_PANPA UniProtKB/TrEMBL
  A0A2R8ZTT7_PANPA UniProtKB/TrEMBL