HLTF (helicase like transcription factor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: HLTF (helicase like transcription factor) Pan paniscus
Analyze
Symbol: HLTF
Name: helicase like transcription factor
RGD ID: 11701879
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN DNA repair (inferred); mRNA transcription by RNA polymerase II (inferred); positive regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH aceruloplasminemia (ortholog); glycogen storage disease XV (ortholog); Kidney Neoplasms (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); RNA polymerase II transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: helicase-like transcription factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13153,632,319 - 153,688,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3153,632,319 - 153,688,951 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HLTF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13153,632,319 - 153,688,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3153,632,319 - 153,688,951 (-)Ensemblpanpan1.1panPan2
HLTF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383149,030,063 - 149,086,533 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3149,030,127 - 149,086,554 (-)EnsemblGRCh38hg38GRCh38
GRCh373148,747,850 - 148,804,320 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363150,230,594 - 150,287,031 (-)NCBINCBI36Build 36hg18NCBI36
Build 343150,230,611 - 150,287,015NCBI
Celera3147,158,179 - 147,214,609 (-)NCBICelera
Cytogenetic Map3q24NCBI
HuRef3146,119,870 - 146,176,257 (-)NCBIHuRef
CHM1_13148,710,947 - 148,767,418 (-)NCBICHM1_1
T2T-CHM13v2.03151,780,777 - 151,837,250 (-)NCBIT2T-CHM13v2.0
Hltf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39320,111,959 - 20,172,655 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl320,111,975 - 20,172,654 (+)EnsemblGRCm39 Ensembl
GRCm38320,057,808 - 20,118,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl320,057,811 - 20,118,490 (+)EnsemblGRCm38mm10GRCm38
MGSCv37319,957,811 - 20,018,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36320,249,962 - 20,310,527 (+)NCBIMGSCv36mm8
Celera320,047,166 - 20,107,713 (+)NCBICelera
Cytogenetic Map3A2NCBI
cM Map36.15NCBI
Hltf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82104,478,725 - 104,538,531 (+)NCBIGRCr8
mRatBN7.22102,549,724 - 102,609,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2102,549,724 - 102,609,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2109,063,231 - 109,122,470 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02107,184,391 - 107,243,629 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02102,148,291 - 102,207,981 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02104,854,571 - 104,914,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2104,854,572 - 104,914,173 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02124,574,548 - 124,634,389 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,202,487 - 105,262,107 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12105,148,839 - 105,205,382 (+)NCBI
Celera297,919,578 - 97,979,241 (+)NCBICelera
Cytogenetic Map2q24NCBI
Hltf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554748,412,136 - 8,486,752 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554748,411,912 - 8,488,938 (+)NCBIChiLan1.0ChiLan1.0
HLTF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12343,868,896 - 43,918,616 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2343,870,939 - 43,918,436 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2343,734,282 - 43,783,354 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02344,498,185 - 44,547,255 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2344,498,189 - 44,547,213 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12344,086,465 - 44,136,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02344,134,925 - 44,184,505 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02344,389,026 - 44,438,712 (-)NCBIUU_Cfam_GSD_1.0
Hltf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560283,155,157 - 83,202,437 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365196,531,571 - 6,582,081 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365196,531,549 - 6,579,724 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HLTF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1389,261,205 - 89,333,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11389,261,199 - 89,333,020 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21397,254,690 - 97,326,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HLTF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11541,621,349 - 41,676,185 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1541,621,456 - 41,674,120 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604114,463,704 - 14,518,550 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hltf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473026,257,609 - 26,333,936 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473026,255,426 - 26,334,176 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000038126   ⟹   ENSPPAP00000015436
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3153,632,319 - 153,688,951 (-)Ensembl
RefSeq Acc Id: XM_003826487   ⟹   XP_003826535
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBI
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBI
PanPan1.13153,632,319 - 153,688,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951881   ⟹   XP_008950129
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBI
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBI
PanPan1.13153,632,319 - 153,688,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951882   ⟹   XP_008950130
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBI
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBI
PanPan1.13153,632,324 - 153,688,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951883   ⟹   XP_008950131
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,651 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,381 (-)NCBI
Mhudiblu_PPA_v03146,054,371 - 146,111,147 (-)NCBI
PanPan1.13153,632,319 - 153,688,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951884   ⟹   XP_008950132
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,742 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,472 (-)NCBI
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBI
PanPan1.13153,632,324 - 153,688,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951885   ⟹   XP_008950133
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,681 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,411 (-)NCBI
Mhudiblu_PPA_v03146,054,371 - 146,111,150 (-)NCBI
PanPan1.13153,632,324 - 153,688,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055110596   ⟹   XP_054966571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,651 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,381 (-)NCBI
RefSeq Acc Id: XM_055110597   ⟹   XP_054966572
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22146,925,896 - 146,982,681 (-)NCBI
NHGRI_mPanPan13146,930,616 - 146,987,411 (-)NCBI
RefSeq Acc Id: XP_008950131   ⟸   XM_008951883
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003826535   ⟸   XM_003826487
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008950129   ⟸   XM_008951881
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ADQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008950133   ⟸   XM_008951885
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008950132   ⟸   XM_008951884
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008950130   ⟸   XM_008951882
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ADQ8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000015436   ⟸   ENSPPAT00000038126
RefSeq Acc Id: XP_054966572   ⟸   XM_055110597
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054966571   ⟸   XM_055110596
- Peptide Label: isoform X2
Protein Domains
Helicase ATP-binding   Helicase C-terminal   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030858 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038126.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.30.70.2330 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  HIRAN UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  SNF2_RAD54_helicase_TF UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene HLTF ENTREZGENE
PANTHER HELICASE-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION TERMINATION FACTOR 2-RELATED UniProtKB/TrEMBL
Pfam Helicase_C UniProtKB/TrEMBL
  HIRAN UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
  HIRAN UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9ADQ8 ENTREZGENE, UniProtKB/TrEMBL