CVCL_ZW90 - Rat Genome Database

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Cell Line : CVCL_ZW90 (HuH-7-END) Homo sapiens

Symbol: CVCL_ZW90
Name: HuH-7-END
RGD ID: 40818878
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Gender: Male
Characteristics: Characteristics: Transfected with pJC126, a plasmid harboring a 1.1-fold cDNA copy of the HDV antigenome; Virology: Persistently replicates and secretes hepatitis delta virus (HDV)
Genomic Alteration: Sequence variation: Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line); Sequence variation: Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line); Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line); Transfected with: HGNC; 10905; SLC10A1; Transfected with: UniProtKB; P03138; Hepatitis B virus genotype D subtype ayw envelope protein (HBsAg); Transfected with: UniProtKB; P33967; B.cereus Bsr; Transfected with: UniProtKB; P00552; Transposon Tn5 neo; Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR)
Related Genes: SLC10A1  
Derived From Cell Lines: CVCL_0336 (Huh-7)
Aliases: HuH7-HDV-Env-NTCP clone B1
Disease(s): adult hepatocellular carcinoma (DOID:0070328) [NCI:C7956,ORDO:210159]

References
Additional References at PubMed
PMID:31292511  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_ZW90 CELLOSAURUS
Cellosaurus CVCL_ZW90 CELLOSAURUS
NCIt C7956 CELLOSAURUS
Orphanet 210159 CELLOSAURUS
Wikidata Q102114176 CELLOSAURUS