CVCL_D4TH - Rat Genome Database

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Cell Line : CVCL_D4TH (HuH7-SLC38A4-KO-c1) Homo sapiens

Symbol: CVCL_D4TH
Name: HuH7-SLC38A4-KO-c1
RGD ID: 405099920
Cell Line Type: cancer cell line
Origin: Population: Japanese; Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Gender: Male
Genomic Alteration: Knockout cell: Method=CRISPR/Cas9; HGNC; 14679; SLC38A4; Sequence variation: Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line); Sequence variation: Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line); Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line); Transfected with: UniProtKB; P00552; Transposon Tn5 neo
Groups: Part of: Research Empowerment on Solute Carriers (RESOLUTE) KO cell line panel
Related Genes: SLC38A4  
Derived From Cell Lines: CVCL_0336 (Huh-7)
Aliases: CE05RW-K
Disease(s): adult hepatocellular carcinoma (DOID:0070328) [NCI:C7956,ORDO:210159]

References

Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_D4TH CELLOSAURUS
NCIt C7956 CELLOSAURUS
Orphanet 210159 CELLOSAURUS