CVCL_D204 - Rat Genome Database

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Cell Line : CVCL_D204 (FLC-4) Homo sapiens

Symbol: CVCL_D204
Name: FLC-4
RGD ID: 21152291
Cell Line Type: cancer cell line
Origin: Population: Japanese
Gender: Male
Research Use: Omics: Transcriptome analysis by microarray
Genomic Alteration: Sequence variation: Mutation; HGNC; 173; ACVR2A; Simple; p.Cys78Ter (c.234T>A); Zygosity=Unspecified (from parent cell line); Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line); Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Homozygous (from parent cell line)
Caution: Caution: FLC-4 is often stated to be synonymous with JHH-4 (Cellosaurus=CVCL_2787), but the patent reference (Patent=US5804441) seems to indicate that FLC-4 is derived from JHH-4 and has a different karyotype.
Groups: Group: Patented cell line; Registration: International Depositary Authority, Japanese National Institute of Bioscience and Human-Technology, Agency of Industrial Science and Technology; FERM BP-5165
Derived From Cell Lines: CVCL_2787 (JHH-4)
Aliases: FLC4; Functional Liver Cell-4
Disease(s): adult hepatocellular carcinoma (DOID:0070328) [NCI:C7956,ORDO:210159]
hepatitis C (DOID:1883) [NCI:C3098]

References
Additional References at PubMed
PMID:17241388   PMID:21960466  


Additional Information

Database Acc Id Source(s)
cancercelllines CVCL_D204 CELLOSAURUS
Cellosaurus CVCL_D204 CELLOSAURUS
COSMIC Samples 2321031 CELLOSAURUS
NCIt C3098 CELLOSAURUS
  C7956 CELLOSAURUS
Orphanet 210159 CELLOSAURUS
Wikidata Q54834981 CELLOSAURUS