CVCL_YK40 - Rat Genome Database

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Cell Line : CVCL_YK40 (U2OS CHRM5 DAG-Nomad) Homo sapiens

Symbol: CVCL_YK40
Name: U2OS CHRM5 DAG-Nomad
RGD ID: 21088873
Cell Line Type: cancer cell line
Origin: Population: Caucasian; Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Gender: Female
Characteristics: Characteristics: In absence of DAG, the fluorescent biosensor is localized in the cellular membrane An increase in this second messenger concentration leads to change in the structural folding of Nomad biosensor that promotes its cellular relocation in the vesicular trafficking of the cells.
Genomic Alteration: Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line); Transfected with: HGNC; 1954; CHRM5; Transfected with: UniProtKB; J9PBR7; Entacmaea quadricolor far-red fluorescent protein eqFP650; Transfected with: UniProtKB; P00552; Transposon Tn5 neo; Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR)
Related Genes: CHRM5  
Derived From Cell Lines: CVCL_0042 (U2OS)
Aliases: DAG-NOMAD Muscarinic 5; DAGNomad M5
Disease(s): osteosarcoma (DOID:3347) [NCI:C9145,ORDO:668]

References

Additional Information

Database Acc Id Source(s)
Cellosaurus CVCL_YK40 CELLOSAURUS
Innoprot P70603 CELLOSAURUS
NCIt C9145 CELLOSAURUS
Orphanet 668 CELLOSAURUS
Wikidata Q98133740 CELLOSAURUS