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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1622404
Species: Mus musculus
RGD Object: Gene
Symbol: Defa3
Name: defensin, alpha, 3
Acc ID: CHEBI:8450
Term: procymidone
Definition: An azabicycloalkane that is 1,5-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione in which the amino hydrogen is replaced by a 3,5-dichlorophenyl group. A fungicide widely used in horticulture as a seed dressing, pre-harvest spray or post-harvest dip for the control of various diseases.
Chemical ID: MESH:C035988
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Defa3affects expressionEXP 6480464CTDprocymidone affects the expression of DEFA3 mRNAPMID:36764477
Defa3increases expressionEXP 6480464CTDprocymidone results in increased expression of DEFA3 mRNAPMID:33246813
Defa3multiple interactionsEXP 6480464CTD[tetrachloroisophthalonitrile co-treated with procymidone] results in increased expression of DEFA3 mRNAPMID:33246813
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