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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352326
Species: Homo sapiens
RGD Object: Gene
Symbol: CCT2
Name: chaperonin containing TCP1 subunit 2
Acc ID: CHEBI:63918
Term: artesunate
Definition: An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.
Chemical ID: MESH:C039726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCT2decreases response to substanceEXP 6480464CTDCCT2 mRNA results in decreased susceptibility to artesunatePMID:20144594
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