GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CXCL8 | multiple interactions | EXP | | 6480464 | CTD | wortmannin inhibits the reaction [CXCL8 protein results in increased activity of CXCR2 protein]; wortmannin inhibits the reaction [CXCL8 results in decreased susceptibility to Cisplatin]; wortmannin inhibits the reaction [CXCL8 results in decreased susceptibility to Paclitaxel]; wortmannin inhibits the reaction [CXCL8 results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [nickel subsulfide results in increased expression of CXCL8 mRNA] | PMID:11978798 PMID:12975484 PMID:21742513 | | ||||||||||||||||||||||
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