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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317785
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Acc ID: CHEBI:50438
Term: phenprocoumon
Definition: A hydroxycoumarin that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenylpropyl group.
Chemical ID: MESH:D010644
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c65affects response to substanceISOCYP2C9 (Homo sapiens)6480464CTDCYP2C9 gene polymorphism affects the susceptibility to PhenprocoumonPMID:18698879
Cyp2c65increases metabolic processingISOCYP2C9 (Homo sapiens)6480464CTDCYP2C9 protein results in increased metabolism of PhenprocoumonPMID:19082874
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