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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318852
Species: Mus musculus
RGD Object: Gene
Symbol: Reck
Name: reversion-inducing-cysteine-rich protein with kazal motifs
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Reckaffects expressionISORECK (Homo sapiens)6480464CTDDecitabine affects the expression of RECK mRNAPMID:17233834
Reckaffects methylationISORECK (Homo sapiens)6480464CTDDecitabine affects the methylation of RECK promoterPMID:17443689
Reckmultiple interactionsISORECK (Homo sapiens)6480464CTD[Decitabine affects the methylation of RECK promoter] which affects the expression of RECK mRNA; Decitabine inhibits the reaction [sodium arsenite results in decreased expression of RECK mRNA]; Decitabine inhibits the reaction [sodium arsenite results in decreased expression of RECK protein]PMID:17443689 PMID:21167264
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