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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10787
Species: Mus musculus
RGD Object: Gene
Symbol: Il17a
Name: interleukin 17A
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il17aincreases expressionEXP 6480464CTDGlucose results in increased expression of IL17A mRNAPMID:18310510
Il17aincreases secretionEXP 6480464CTDGlucose results in increased secretion of IL17A proteinPMID:18310510
Il17amultiple interactionsEXP 6480464CTDCycloheximide inhibits the reaction [Glucose results in increased secretion of IL17A protein]; Dactinomycin inhibits the reaction [Glucose results in increased secretion of IL17A protein]; resveratrol inhibits the reaction [Glucose results in increased expression of IL17A mRNA]; resveratrol inhibits the reaction [Glucose results in increased secretion of IL17A protein]PMID:18310510
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