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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561983
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Muc5b
Name: mucin 5B, oligomeric mucus/gel-forming
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Muc5bdecreases expressionISOMUC5B (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of MUC5B mRNAPMID:32201329
Muc5bdecreases expressionISOMuc5b (Mus musculus)6480464CTDsodium arsenite results in decreased expression of MUC5B mRNAPMID:18812580
Muc5bmultiple interactionsISOMUC5B (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of and results in decreased secretion of MUC5B protein; Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of MUC5B mRNA]PMID:32201329
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