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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68656
Species: Mus musculus
RGD Object: Gene
Symbol: Dclk1
Name: doublecortin-like kinase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dclk1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of DCLK1 mRNAPMID:18343893 PMID:26377647
Dclk1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of DCLK1 mRNAPMID:19933214
Dclk1increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of DCLK1 mRNAPMID:15328365 PMID:23994337
Dclk1multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DCLK1 mRNAPMID:17942748
Dclk1affects expressionISODclk1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of DCLK1 mRNAPMID:34747641
Dclk1increases expressionISODCLK1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of DCLK1 mRNAPMID:19619570 PMID:20106945
Dclk1multiple interactionsISODCLK1 (Homo sapiens)6480464CTD[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of DCLK1 mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DCLK1 mRNAPMID:19619570 PMID:26159488
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