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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68563
Species: Mus musculus
RGD Object: Gene
Symbol: Slc7a2
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc7a2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SLC7A2 mRNAPMID:21570461 PMID:26377647 PMID:28922406
Slc7a2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC7A2 mRNAPMID:19770486 PMID:19933214
Slc7a2multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin affects the methylation of SLC7A2 intron] which results in decreased expression of SLC7A2 mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC7A2 mRNAPMID:17942748 PMID:33017471
Slc7a2affects expressionISOSlc7a2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC7A2 mRNAPMID:22298810 PMID:32109520
Slc7a2decreases expressionISOSlc7a2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC7A2 mRNAPMID:21215274 PMID:32277265 PMID:33387578
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