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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620178
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf23
Name: fibroblast growth factor 23
Acc ID: CHEBI:26710
Term: sodium chloride
Definition: An inorganic chloride salt having sodium(1+) as the counterion.
Chemical ID: MESH:D012965
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf23decreases exportEXP 6480464CTDSodium Chloride results in decreased export of FGF23 proteinPMID:37992803
Fgf23decreases expressionEXP 6480464CTDSodium Chloride results in decreased expression of FGF23 mRNAPMID:37992803
Fgf23increases expressionEXP 6480464CTDSodium Chloride deficiency results in increased expression of FGF23 mRNA; Sodium Chloride deficiency results in increased expression of FGF23 proteinPMID:37992803
Fgf23multiple interactionsEXP 6480464CTDMannitol inhibits the reaction [Sodium Chloride deficiency results in increased expression of FGF23 mRNA]; Mannitol inhibits the reaction [Sodium Chloride deficiency results in increased expression of FGF23 protein]; NFAT5 protein affects the reaction [Sodium Chloride results in decreased export of FGF23 protein]PMID:37992803
Fgf23decreases expressionISOFgf23 (Mus musculus)6480464CTDSodium Chloride results in decreased expression of FGF23 mRNAPMID:37992803
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