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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731867
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2a5
Name: cytochrome P450, family 2, subfamily a, polypeptide 5
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2a5increases expressionEXP 6480464CTDCadmium results in increased expression of CYP2A5 mRNAPMID:15041070 PMID:16183037
Cyp2a5multiple interactionsEXP 6480464CTDCadmium results in increased expression of and results in increased activity of CYP2A5 protein; NFE2L2 protein promotes the reaction [Cadmium results in increased expression of CYP2A5 mRNA]PMID:15041070 PMID:16183037
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