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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734231
Species: Homo sapiens
RGD Object: Gene
Symbol: SST
Name: somatostatin
Acc ID: CHEBI:176788
Term: dizocilpine maleate
Definition: A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid.
Chemical ID: MESH:D016291
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SSTdecreases expressionISOSst (Rattus norvegicus)6480464CTDDizocilpine Maleate results in decreased expression of SST mRNA; Dizocilpine Maleate results in decreased expression of SST proteinPMID:16567023
SSTmultiple interactionsISOSst (Rattus norvegicus)6480464CTDClozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of SST mRNA]; Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of SST protein]PMID:16567023
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