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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553598
Species: Mus musculus
RGD Object: Gene
Symbol: Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpa1increases activityISOTrpa1 (Rattus norvegicus)6480464CTDFormaldehyde results in increased activity of TRPA1 proteinPMID:19847360
Trpa1increases activityISOTRPA1 (Homo sapiens)6480464CTDFormaldehyde results in increased activity of TRPA1 proteinPMID:21591660
Trpa1multiple interactionsISOTrpa1 (Rattus norvegicus)6480464CTD2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [Formaldehyde results in increased activity of TRPA1 protein]PMID:19847360
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