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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557397
Species: Mus musculus
RGD Object: Gene
Symbol: Lcor
Name: ligand dependent nuclear receptor corepressor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcorincreases expressionISOLCOR (Homo sapiens)6480464CTDEstradiol results in increased expression of LCOR mRNAPMID:23019147 PMID:31614463
Lcormultiple interactionsISOLCOR (Homo sapiens)6480464CTDEstradiol promotes the reaction [ESR1 protein binds to LCOR protein]PMID:23665804 PMID:29389661 PMID:32088792
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