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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735404
Species: Homo sapiens
RGD Object: Gene
Symbol: ALB
Name: albumin
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALBaffects bindingEXP 6480464CTD[Acrolein binds to Acrolein] which binds to ALB protein; dinitrophenylhydrazine binds to [Acrolein binds to ALB protein]; Hydralazine binds to [Acrolein binds to ALB protein]PMID:15207723 PMID:32530271
ALBmultiple interactionsEXP 6480464CTD[Acrolein binds to ALB protein] which results in increased expression of HMOX1 mRNA; Acrolein binds to and results in increased oxidation of ALB protein; ALB protein inhibits the reaction [Acrolein results in increased expression of ATF3 mRNA]; ALB protein inhibits the reaction [Acrolein results in increased expression of HMOX1 mRNA]; Hydralazine inhibits the reaction [[Acrolein binds to ALB protein] which results in increased expression of HMOX1 mRNA]PMID:32530271
ALBmultiple interactionsISOAlb (Mus musculus)6480464CTDAcrolein binds to and results in increased oxidation of ALB proteinPMID:32530271
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