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GENE - TERM ANNOTATION REPORT

RGD ID: 9014683
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Pik3r1
Name: phosphoinositide-3-kinase regulatory subunit 1
Acc ID: DOID:3068
Term: glioblastoma
Definition: A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes. (DO)
Definition Source(s): http://cancergenome.nih.gov/cancersselected/glioblastomamultiforme "DO" "DO", http://en.wikipedia.org/wiki/Glioblastoma_multiforme "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/20129251 "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/23029035 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3r1 ISOPIK3R1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: GlioblastomaPMID:19962457 PMID:25157968 PMID:26619011
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