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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737448
Species: Mus musculus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:37187
Term: lead nitrate
Definition: A lead coordination entity that has formula N2O6Pb.
Chemical ID: MESH:C017461
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catdecreases activityEXP 6480464CTDlead nitrate results in decreased activity of CAT proteinPMID:23451106
Catmultiple interactionsEXP 6480464CTDmangiferin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]PMID:23451106
Catdecreases activityISOCat (Rattus norvegicus)6480464CTDlead nitrate results in decreased activity of CAT proteinPMID:23315276 PMID:24987671
Catmultiple interactionsISOCat (Rattus norvegicus)6480464CTDAshwagandha inhibits the reaction [lead nitrate results in decreased activity of CAT protein]; puerarin inhibits the reaction [lead nitrate results in decreased activity of CAT protein]PMID:23315276 PMID:24987671
Catmultiple interactionsISOCAT (Homo sapiens)6480464CTD[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein; titanium dioxide inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased activity of CAT protein]PMID:30738203
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