GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | increases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | alpha-Tocopherol results in increased activity of CAT protein | PMID:18547560 PMID:19941068 | Cat | increases expression | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | alpha-Tocopherol results in increased expression of CAT protein | PMID:22732938 | Cat | increases expression | ISO | CAT (Homo sapiens) | 6480464 | CTD | alpha-Tocopherol results in increased expression of CAT mRNA; alpha-Tocopherol results in increased expression of CAT protein | PMID:19083475 | Cat | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Curcumin co-treated with alpha-Tocopherol] inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [Copper Sulfate results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Camptothecin results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein] | PMID:16979807 PMID:19464315 PMID:20194575 PMID:21322096 PMID:25233897 PMID:25304969 PMID:27823922 PMID:30057697 PMID:31022331 PMID:9306888 | Cat | multiple interactions | ISO | CAT (Homo sapiens) | 6480464 | CTD | alpha-Tocopherol inhibits the reaction [Hexachlorobenzene results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased expression of and results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAT mRNA] | PMID:26365763 PMID:36058301 | |
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