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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736793
Species: Homo sapiens
RGD Object: Gene
Symbol: GCLC
Name: glutamate-cysteine ligase catalytic subunit
Acc ID: CHEBI:78673
Term: cumene hydroperoxide
Definition: A peroxol that is cumene in which the alpha-hydrogen is replaced by a hydroperoxy group.
Chemical ID: MESH:C007164
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GCLCincreases expressionISOGclc (Mus musculus)6480464CTDcumene hydroperoxide results in increased expression of GCLC mRNAPMID:30547568
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