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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736747
Species: Homo sapiens
RGD Object: Gene
Symbol: ALDH1A1
Name: aldehyde dehydrogenase 1 family member A1
Acc ID: CHEBI:39178
Term: clothianidin
Definition: An N-nitro compound consisting of 2-nitroguanidine having a (2-chloro-1,3-thiazol-5-yl)methyl group at position 1 and a methyl group at position 3.
Chemical ID: MESH:C480342
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALDH1A1increases expressionISOAldh1a1 (Rattus norvegicus)6480464CTDclothianidin results in increased expression of ALDH1A1 mRNAPMID:33426623
ALDH1A1multiple interactionsISOAldh1a1 (Rattus norvegicus)6480464CTD[enilconazole co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA; [thiacloprid co-treated with clothianidin] results in increased expression of ALDH1A1 mRNAPMID:33426623
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