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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736545
Species: Homo sapiens
RGD Object: Gene
Symbol: ALAD
Name: aminolevulinate dehydratase
Acc ID: CHEBI:6504
Term: lithium carbonate
Definition: A carbonate salt that has formula CO3.2Li.
Chemical ID: MESH:D016651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALADdecreases activityISOAlad (Rattus norvegicus)6480464CTDLithium Carbonate results in decreased activity of ALAD proteinPMID:19083387 PMID:28988373
ALADmultiple interactionsISOAlad (Rattus norvegicus)6480464CTDLithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of ALAD protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of ALAD protein]; Zinc Sulfate inhibits the reaction [Lithium Carbonate results in decreased activity of ALAD protein]PMID:19083387 PMID:28988373
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