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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736305
Species: Mus musculus
RGD Object: Gene
Symbol: Lgals3
Name: lectin, galactose binding, soluble 3
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lgals3increases expressionEXP 6480464CTDDoxorubicin results in increased expression of LGALS3 mRNAPMID:36227756
Lgals3decreases response to substanceISOLGALS3 (Homo sapiens)6480464CTDLGALS3 mRNA results in decreased susceptibility to DoxorubicinPMID:16322897
Lgals3increases expressionISOLGALS3 (Homo sapiens)6480464CTDDoxorubicin results in increased expression of LGALS3 mRNAPMID:29803840
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