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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736304
Species: Homo sapiens
RGD Object: Gene
Symbol: LGALS3
Name: galectin 3
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LGALS3multiple interactionsEXP 6480464CTDarsenite inhibits the reaction [G3BP1 protein binds to LGALS3 protein]; arsenite promotes the reaction [G3BP1 protein binds to LGALS3 mRNA]PMID:32406909
LGALS3decreases expressionISOLgals3 (Mus musculus)6480464CTDarsenite results in decreased expression of LGALS3 proteinPMID:37955338
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