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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736173
Species: Mus musculus
RGD Object: Gene
Symbol: Becn1
Name: beclin 1, autophagy related
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Becn1multiple interactionsEXP 6480464CTD[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of BECN1 protein; [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BECN1 protein; [Oxygen deficiency co-treated with Oxygen] results in decreased expression of BECN1 protein; epigallocatechin gallate inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BECN1 protein]; Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of BECN1 protein]; SIRT1 promotes the reaction [SNHG12 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of BECN1 protein]]; SNHG12 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of BECN1 protein]; SNHG12 mRNA promotes the reaction [Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of BECN1 mRNA]]; YAP1 promotes the reaction [SNHG12 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of BECN1 protein]]PMID:34740634 PMID:35307376
Becn1decreases expressionISOBecn1 (Rattus norvegicus)6480464CTDOxygen deficiency results in decreased expression of BECN1 mRNAPMID:28983604
Becn1multiple interactionsISOBecn1 (Rattus norvegicus)6480464CTDsanggenone C inhibits the reaction [Oxygen deficiency results in decreased expression of BECN1 mRNA]PMID:28983604
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