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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736172
Species: Homo sapiens
RGD Object: Gene
Symbol: SHBG
Name: sex hormone binding globulin
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SHBGdecreases expressionEXP 6480464CTDCopper results in decreased expression of SHBG mRNAPMID:19685012
SHBGmultiple interactionsEXP 6480464CTDCopper promotes the reaction [Estradiol results in increased expression of SHBG mRNA]; Estradiol promotes the reaction [Copper affects the expression of SHBG mRNA]PMID:19685012
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