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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736160
Species: Homo sapiens
RGD Object: Gene
Symbol: SYK
Name: spleen associated tyrosine kinase
Acc ID: CHEBI:16978
Term: leukotriene C4
Definition: A leukotriene that is (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid in which a glutathionyl group is attached at position 6 via a sulfide linkage.
Chemical ID: MESH:D017997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SYKmultiple interactionsEXP 6480464CTDSYK protein promotes the reaction [Peptidoglycan results in increased metabolism of Leukotriene C4]; SYK protein promotes the reaction [Zymosan results in increased metabolism of Leukotriene C4]PMID:17030235
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