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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735963
Species: Mus musculus
RGD Object: Gene
Symbol: Slco1a4
Name: solute carrier organic anion transporter family, member 1a4
Acc ID: CHEBI:28865
Term: taurocholic acid
Definition: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Chemical ID: MESH:D013656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slco1a4affects transportEXP 6480464CTDSLCO1A4 protein affects the transport of Taurocholic AcidPMID:19833843
Slco1a4affects uptakeEXP 6480464CTDSLCO1A4 protein affects the uptake of Taurocholic AcidPMID:21561886
Slco1a4increases expressionEXP 6480464CTDTaurocholic Acid results in increased expression of SLCO1A4 mRNAPMID:27160211
Slco1a4increases uptakeISOSlco1a4 (Rattus norvegicus)6480464CTDSLCO1A2 protein results in increased uptake of Taurocholic AcidPMID:19464309
Slco1a4multiple interactionsISOSlco1a4 (Rattus norvegicus)6480464CTDBile Acids and Salts inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid]PMID:19464309
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