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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735483
Species: Mus musculus
RGD Object: Gene
Symbol: Tph1
Name: tryptophan hydroxylase 1
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tph1increases expressionEXP 6480464CTDDextran Sulfate results in increased expression of TPH1 proteinPMID:30611738
Tph1multiple interactionsEXP 6480464CTDGranisetron inhibits the reaction [Serotonin inhibits the reaction [Dextran Sulfate results in increased expression of TPH1 protein]]; Serotonin inhibits the reaction [Dextran Sulfate results in increased expression of TPH1 protein]PMID:30611738
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