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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735435
Species: Homo sapiens
RGD Object: Gene
Symbol: SULT1A1
Name: sulfotransferase family 1A member 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SULT1A1decreases expressionISOSult1a1 (Rattus norvegicus)6480464CTDPhenobarbital results in decreased expression of SULT1A1 mRNAPMID:9566755
SULT1A1increases expressionISOSult1a1 (Rattus norvegicus)6480464CTDPhenobarbital results in increased expression of SULT1A1 mRNAPMID:19631232
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