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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735346
Species: Homo sapiens
RGD Object: Gene
Symbol: JUND
Name: JunD proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNDincreases expressionISOJund (Rattus norvegicus)6480464CTDmethylmercuric chloride results in increased expression of JUND mRNA; methylmercuric chloride results in increased expression of JUND proteinPMID:29522201
JUNDmultiple interactionsISOJund (Rattus norvegicus)6480464CTDJUND affects the reaction [methylmercuric chloride results in increased expression of REST mRNA]; JUND affects the reaction [methylmercuric chloride results in increased expression of SP4 mRNA]; methylmercuric chloride promotes the reaction [JUND protein binds to REST promoter]; methylmercuric chloride promotes the reaction [JUND protein binds to SP4 promoter]; MIR206 inhibits the reaction [methylmercuric chloride promotes the reaction [JUND protein binds to REST promoter]]; MIR206 inhibits the reaction [methylmercuric chloride promotes the reaction [JUND protein binds to SP4 promoter]]PMID:29522201
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