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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735038
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cct3
Name: chaperonin containing TCP1 subunit 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cct3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CCT3 mRNAPMID:34947998
Cct3increases expressionEXP 6480464CTDbisphenol A results in increased expression of CCT3 mRNAPMID:25181051
Cct3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CCT3 mRNAPMID:36041667
Cct3decreases expressionISOCCT3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CCT3 mRNA; bisphenol A results in decreased expression of CCT3 proteinPMID:29275510 PMID:33024228 PMID:34186270
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