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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734356
Species: Homo sapiens
RGD Object: Gene
Symbol: JUN
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:7507
Term: neomycin
Definition: A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections.
Chemical ID: MESH:D009355
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNincreases expressionISOJun (Rattus norvegicus)6480464CTDNeomycin results in increased expression of JUN protein modified formPMID:10627579
JUNmultiple interactionsISOJun (Rattus norvegicus)6480464CTD3,9-bis((ethylthio)methyl)-K-252a inhibits the reaction [Neomycin results in increased expression of JUN protein modified form]PMID:10627579
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